September 2020

Eckes T, Trautmann S, Djudjaj S, Beyer S, Patyna S, Schwalm S, Gauer S, Thomas D, Schaefer L, Boor P, Koch A Pfeilschifter J. Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys. Biochim Biophys Acta Mol Cell Biol Lipids:158821, 2020.
Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, Knapp S, Carles F, Bonnet P, Buron F, Routier S Ruchaud S. Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. J Enzyme Inhib Med Chem 35:1840-1853, 2020.
Giannitsis E, Slagman A, Hamm CW, Gehrig S, Vollert JO Huber K. Copeptin combined with either non-high sensitivity or high sensitivity cardiac troponin for instant rule-out of suspected non-ST segment elevation myocardial infarction. Biomarkers:1-33, 2020.
Hiesinger K, Kramer JS, Beyer S, Eckes T, Brunst S, Flauaus C, Wittmann SK, Weizel L, Kaiser A, Kretschmer SBM, George S, Angioni C, Heering J, Geisslinger G, Schubert-Zsilavecz M, Schmidtko A, Pogoryelov D, Pfeilschifter J, Hofmann B, Steinhilber D, Schwalm S Proschak E. Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase. J Med Chem, 2020.
Mia I, Le M, Arendt C, Brand D, Bremekamp S, D’angelo T, Puntmann VO Nagel E. Quantitative perfusion-CMR is significantly influenced by the placement of the arterial input function. Int J Cardiovasc Imaging, 2020.
Rieth AJ, Hamm CW, Wanner C, Mitrovic V Keller T. [Heart failure protection by SGLT2 inhibitors in patients with type 2 diabetes mellitus: evidence and possible mechanisms : A systematic review]. Herz, 2020.
Röhm S, Schröder M, Dwyer JE, Widdowson CS, Chaikuad A, Berger BT, Joerger AC, Krämer A, Harbig J, Dauch D, Kudolo M, Laufer S, Bagley MC Knapp S. Selective targeting of the αC and DFG-out pocket in p38 MAPK. Eur J Med Chem 208:112721, 2020.
Durko AP, Pibarot P, Atluri P, Bapat V, Cameron DE, Casselman FPA, Chen EP, Dahle G, Elefteriades JA, Lancellotti P, Prager RL, Rosenhek R, Speir A, Stijnen M, Tasca G, Yoganathan A, Walther T De Paulis R. Essential Information on Surgical Heart Valve Characteristics for Optimal Valve Prosthesis Selection: Expert Consensus Document From the European Association for Cardio-Thoracic Surgery (EACTS)-The Society of Thoracic Surgeons (STS)-American Association for Thoracic Surgery (AATS) Valve Labelling Task Force. Ann Thorac Surg, 2020.
Durko AP, Pibarot P, Atluri P, Bapat V, Cameron DE, Casselman FPA, Chen EP, Dahle G, Elefteriades JA, Lancellotti P, Prager RL, Rosenhek R, Speir A, Stijnen M, Tasca G, Yoganathan A, Walther T De Paulis R. Essential information on surgical heart valve characteristics for optimal valve prosthesis selection: expert consensus document from the European Association for Cardio-Thoracic Surgery (EACTS)-The Society of Thoracic Surgeons (STS)-American Association for Thoracic Surgery (AATS) Valve Labelling Task Force. Eur J Cardiothorac Surg, 2020.
Hahnefeld L, Kornstädt L, Kratz D, Ferreirós N, Geisslinger G, Pierre S Scholich K. Lipidomic analysis of local inflammation models shows a specific systemic acute phase response to lipopolysaccharides. Biochim Biophys Acta Mol Cell Biol Lipids:158822, 2020.
Ingelfinger R, Henke M, Roser L, Ulshöfer T, Calchera A, Singh G, Parnham MJ, Geisslinger G, Fürst R, Schmitt I Schiffmann S. Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach. Front Pharmacol 11:1322, 2020.
Ndrepepa G, Kastrati A, Menichelli M, Neumann FJ, Wöhrle J, Bernlochner I, Richardt G, Witzenbichler B, Sibbing D, Gewalt S, Angiolillo DJ, Hamm CW, Hapfelmeier A, Trenk D, Laugwitz KL, Schunkert H, Schüpke S Mayer K. Ticagrelor or Prasugrel in Patients With Acute Coronary Syndromes and Diabetes Mellitus. JACC Cardiovasc Interv 13:2238-2247, 2020.
Pfeffer T, Lignelli E, Inoue H, Mižíková I, Surate Solaligue DE, Steenbock H, Myti D, Vadász I, Herold S, Brinckmann J, Seeger W Morty RE. Minoxidil cannot be used to target lysyl hydroxylases during post‑natal mouse lung development: a cautionary note. J Pharmacol Exp Ther, 2020.
Sirait-Fischer E, Olesch C, Fink AF, Berkefeld M, Huard A, Schmid T, Takeda K, Brüne B Weigert A. Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model. Front Oncol 10:1771, 2020.
Gao C, Takahashi K, Garg S, Hara H, Wang R, Kawashima H, Ono M, Montalescot G, Haude M, Slagboom T, Vranckx P, Valgimigli M, Windecker S, Hamm C, Steg PG, Storey R, Van Geuns RJ, Tao L, Onuma Y Serruys PW. Regional variation in patients and outcomes in the GLOBAL LEADERS trial. Int J Cardiol, 2020.
Gragnano F, Heg D, Franzone A, Mcfadden EP, Leonardi S, Piccolo R, Vranckx P, Branca M, Serruys PW, Benit E, Liebetrau C, Janssens L, Ferrario M, Zurakowski A, Diletti R, Dominici M, Huber K, Slagboom T, Buszman P, Bolognese L, Tumscitz C, Bryniarski K, Aminian A, Vrolix M, Petrov I, Garg S, Naber C, Prokopczuk J, Hamm C, Steg PG, Jüni P, Windecker S Valgimigli M. PRECISE-DAPT score for bleeding risk prediction in patients on dual or single antiplatelet regimens: insights from the GLOBAL LEADERS and GLASSY. Eur Heart J Cardiovasc Pharmacother, 2020.
Harrington L, Alexander LT, Knapp S Bayley H. Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules. Methods Mol Biol 2186:95-114, 2021.
Hotter G, Mastora C, Jung M, Brüne B, Carbonell T, Josa C, Pérez-Calvo JI, Cruzado JM, Guiteras R Sola A. The influenza virus NS1A binding protein gene modulates macrophages response to cytokines and phagocytic potential in inflammation. Sci Rep 10:15302, 2020.
Jiang Z, Carlantoni C, Allanki S, Ebersberger I Stainier DYR. Tek/Tie2 is not required for cardiovascular development in zebrafish. Development, 2020.
Klann K Münch C. Unbiased translation proteomics upon cell stress. Mol Cell Oncol 7:1763150, 2020.
Kontarakis Z Stainier DYR. Genetics in Light of Transcriptional Adaptation. Trends Genet, 2020. review
Schmid T, Boehm U Braun T. GnRH neurogenesis depends on embryonic pheromone receptor expression. Mol Cell Endocrinol:111030, 2020. review
Weber J, Rajan S, Schremmer C, Chao YK, Krasteva-Christ G, Kannler M, Yildirim A, Brosien M, Schredelseker J, Weissmann N, Grimm C, Gudermann T Dietrich A. TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema. JCI Insight, 2020.
Zarnack K, Balasubramanian S, Gantier MP, Kunetsky V, Kracht M, Schmitz ML Sträßer K. Dynamic mRNP Remodeling in Response to Internal and External Stimuli. Biomolecules 10, 2020. review
Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S Wolf E. PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Nat Chem Biol, 2020.
Blankenbach KV, Claas RF, Aster NJ, Spohner AK, Trautmann S, Ferreirós N, Black JL, Tesmer JJG, Offermanns S, Wieland T Meyer Zu Heringdorf D. Dissecting G(q/11)-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1. Cells 9, 2020.
Boezio GL, Bensimon-Brito A, Piesker J, Guenther S, Helker CS Stainier DY. Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract. Elife 9, 2020.
Haas J, Bloesel D, Bacher S, Kracht M Schmitz ML. Chromatin Targeting of HIPK2 Leads to Acetylation-Dependent Chromatin Decondensation. Front Cell Dev Biol 8:852, 2020.
Juettner NE, Bogen JP, Bauer TA, Knapp S, Pfeifer F, Huettenhain SH, Meusinger R, Kraemer A Fuchsbauer HL. Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway. J Nat Prod, 2020.
Knapp F, Niemann B, Li L, Molenda N, Kracht M, Schulz R Rohrbach S. Differential effects of right and left heart failure on skeletal muscle in rats. J Cachexia Sarcopenia Muscle, 2020.
Ubags NDJ, Alejandre Alcazar MA, Kallapur SG, Knapp S, Lanone S, Lloyd CM, Morty RE, Pattaroni C, Reynaert NL, Rottier RJ, Smits HH, De Steenhuijsen Piters WaA, Strickland DH Collins JJP. Early origins of lung disease: towards an interdisciplinary approach. Eur Respir Rev 29, 2020. review
Vazquez-Armendariz AI, Heiner M, El Agha E, Salwig I, Hoek A, Hessler MC, Shalashova I, Shrestha A, Carraro G, Mengel JP, Günther A, Morty RE, Vadász I, Schwemmle M, Kummer W, Hain T, Goesmann A, Bellusci S, Seeger W, Braun T Herold S. Multilineage murine stem cells generate complex organoids to model distal lung development and disease. Embo j:e103476, 2020
Waidmann O, Pleli T, Weigert A, Imelmann E, Kakoschky B, Schmithals C, Döring C, Frank M, Longerich T, Köberle V, Hansmann ML, Brüne B, Zeuzem S, Piiper A Dikic I. Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis. Sci Rep 10:16264, 2020.
Zheng X, Mansouri S, Krager A, Grimminger F, Seeger W, Pullamsetti SS, Wheelock CE Savai R. Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment. Eur Respir Rev 29, 2020.
Klann K, Bojkova D, Tascher G, Ciesek S, Münch C Cinatl J. Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication. Mol Cell, 2020.
Bojkova D, Wagner JUG, Shumliakivska M, Aslan GS, Saleem U, Hansen A, Luxán G, Günther S, Pham MD, Krishnan J, Harter PN, Ermel UH, Frangakis AS, Milting H, Zeiher AM, Klingel K, Cinatl J, Dendorfer A, Eschenhagen T, Tschöpe C, Ciesek S Dimmeler S. SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes. Cardiovasc Res, 2020.
Buchmann GK, Schürmann C, Warwick T, Schulz MH, Spaeth M, Müller OJ, Schröder K, Jo H, Weissmann N Brandes RP. Deletion of NoxO1 limits atherosclerosis development in female mice. Redox Biol 37:101713, 2020.
Carlantoni C, Allanki S, Kontarakis Z, Rossi A, Piesker J, Günther S Stainier DYR. Tie1 regulates zebrafish cardiac morphogenesis through tolloid-like 1 expression. Dev Biol, 2020.
Elliott P, Cowie MR, Franke J, Ziegler A, Antoniades C, Bax J, Bucciarelli-Ducci C, Flachskampf FA, Hamm C, Jensen MT, Katus H, Maisel A, Mcdonagh T, Mittmann C, Muntendam P, Nagel E, Rosano G, Twerenbold R Zannad F. Development, validation and implementation of biomarker testing in cardiovascular medicine state-of-the-art: Proceedings of the European Society of Cardiology – Cardiovascular Round Table. Cardiovasc Res, 2020.
Erath JW, Aßmus B, Burch A, Bondermann D, Russo AM Kutyifa V. Sustained Ventricular Tachyarrhythmia Termination in a Large Cohort of Women Using Wearable Cardioverter-Defibrillators. JACC Clin Electrophysiol 6:1187-1188, 2020. letter
Färber G, Bleiziffer S, Doenst T, Bon D, Böning A, Weiler H, Herrmann E, Frerker C, Beckmann A, Möllmann H, Ensminger S, Bekeredjian R, Walther T, Harringer W, Katus HA, Hamm CW, Beyersdorf F, Bauer T Fichtlscherer S. Transcatheter or surgical aortic valve implantation in chronic dialysis patients: a German Aortic Valve Registry analysis. Clin Res Cardiol, 2020.
Helker CS, Eberlein J, Wilhelm K, Sugino T, Malchow J, Schuermann A, Baumeister S, Kwon HB, Maischein HM, Potente M, Herzog W Stainier DY. Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state. Elife 9, 2020.
Ono M, Tomaniak M, Koenig W, Khamis R, De Silva R, Chichareon P, Kawashima H, Hara H, Gao C, Wang R, Huber K, Vrolix M, Jasionowicz P, Wykrzykowska JJ, Piek JJ, Jüni P, Hamm C, Steg PG, Windecker S, Onuma Y, Storey RF Serruys PW. Impact of White Blood Cell Count on Clinical Outcomes in Patients Treated with Aspirin-Free Ticagrelor Monotherapy after Percutaneous Coronary Intervention: Insights from the GLOBAL LEADERS Trial. Eur Heart J Cardiovasc Pharmacother, 2020.
Schutt C, Hallmann A, Hachim S, Klockner I, Valussi M, Atzberger A, Graumann J, Braun T Boettger T. Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy. Embo j:e105098, 2020.
Shimoda LA Morty RE. Call for Papers on “Lung diseases in reverse translation: Bedside to the bench”. Am J Physiol Lung Cell Mol Physiol, 2020. editorial
Wolters MC, Schmetzer J, Möser CV, Hahnefeld L, Angioni C, Thomas D, Ferreirós N, Geisslinger G Niederberger E. Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers. Cells 9, 2020.
Wygrecka M, Kosanovic D, Kwapiszewska G Preissner KT. Editorial: Multitasking Biomolecules in Human Pathologies: Known Players on Their Unexpected Journeys. Front Med (Lausanne) 7:478, 2020. editorial
Mathur A, Fernández-Avilés F, Bartunek J, Belmans A, Crea F, Dowlut S, Galiñanes M, Good MC, Hartikainen J, Hauskeller C, Janssens S, Kala P, Kastrup J, Martin J, Menasché P, Sanz-Ruiz R, Ylä-Herttuala S Zeiher A. The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial. Eur Heart J, 2020.
Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber GS, Seeger W Morty RE. Elevated FiO(2) increases SARS-CoV-2 co‑receptor expression in respiratory tract epithelium. Am J Physiol Lung Cell Mol Physiol, 2020.
Nolte CH, Von Rennenberg R, Litmeier S, Scheitz JF, Leistner DM, Blankenberg S, Dichgans M, Katus H, Petzold GC, Pieske B, Regitz-Zagrosek V, Wegscheider K, Zeiher AM, Landmesser U Endres M. PRediction of acute coronary syndrome in acute ischemic StrokE (PRAISE) – protocol of a prospective, multicenter trial with central reading and predefined endpoints. BMC Neurol 20:318, 2020.
Pullamsetti SS, Mamazhakypov A, Weissmann N, Seeger W Savai R. Hypoxia-inducible factor signaling in pulmonary hypertension. J Clin Invest, 2020. review

September 2020

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