New this week in PubMed from CPI Institute

  • Amrhein JA, Beyett TS, Feng WW, Krämer A, Weckesser J, Schaeffner IK, Rana JK, Jänne PA, Eck MJ, Knapp S, Hanke T. Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19. J Med Chem, 2022.
  • Boonsanay V, Mosa MH, Looso M, Weichenhan D, Ceteci F, Pudelko L, Lechel A, Michel CS, Künne C, Farin HF, Plass C, Greten FR. Loss of SUV420H2-dependent chromatin compaction drives right-sided colon cancer progression. Gastroenterology, 2022.
  • Cardeira-Da-Silva J, Bensimon-Brito A, Tarasco M, Brandão AS, Rosa JT, Borbinha J, Almeida PJ, Jacinto A, Cancela ML, Gavaia PJ, Stainier DYR, Laizé V. Fin ray branching is defined by TRAP(+) osteolytic tubules in zebrafish. Proc Natl Acad Sci U S A 119:e2209231119, 2022.
  • Chaikuad A, Zhubi R, Tredup C, Knapp S. Comparative structural analyses of the NHL domains from the human E3 ligase TRIM-NHL family. IUCrJ 9:720-727, 2022.
  • Fuhrmann DC, Becker S, Brüne B. Mitochondrial ferritin expression in human macrophages is facilitated by thrombin-mediated cleavage under hypoxia. FEBS Lett, 2022.
  • Hua Y, Vella G, Rambow F, Allen E, Antoranz Martinez A, Duhamel M, Takeda A, Jalkanen S, Junius S, Smeets A, Nittner D, Dimmeler S, Hehlgans T, Liston A, Bosisio FM, Floris G, Laoui D, Hollmén M, Lambrechts D, Merchiers P, Marine JC, Schlenner S, Bergers G. Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1(+) T lymphocyte niches through a feed-forward loop. Cancer Cell, 2022.
  • Jiang Z, El-Brolosy MA, Serobyan V, Welker JM, Retzer N, Dooley CM, Jakutis G, Juan T, Fukuda N, Maischein HM, Balciunas D, Stainier DYR. Parental mutations influence wild-type offspring via transcriptional adaptation. Sci Adv 8:eabj2029, 2022.
  • Nakayama A, Roquid KA, Iring A, Strilic B, Günther S, Chen M, Weinstein LS, Offermanns S. Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth. J Exp Med 220, 2023.
  • Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP. Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Rep 41:111670, 2022.
  • Peng W, Kepsch A, Kracht TO, Hasan H, Wijayarathna R, Wahle E, Pleuger C, Bhushan S, Günther S, Kauerhof AC, Planinić A, Fietz D, Schuppe HC, Wygrecka M, Loveland KL, Ježek D, Meinhardt A, Hedger MP, Fijak M. Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis. Cell Mol Life Sci 79:602, 2022.
  • Saraswathy VM, Zhou L, Mcadow AR, Burris B, Dogra D, Reischauer S, Mokalled MH. Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish. Cell Rep 41:111705, 2022.
  • Schmitt D, Bozkurt S, Henning-Domres P, Huesmann H, Eimer S, Bindila L, Behrends C, Boyle E, Wilfling F, Tascher G, Münch C, Behl C, Kern A. FACS-mediated isolation of native autophagic vesicles. Autophagy, 2022.
  • Shaban MS, Müller C, Mayr-Buro C, Weiser H, Schmitz ML, Ziebuhr J, Kracht M. Reply to: The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein. Nat Commun 13:6550, 2022. letter
  • Wu Z, Berlemann LA, Bader V, Sehr DA, Dawin E, Covallero A, Meschede J, Angersbach L, Showkat C, Michaelis JB, Münch C, Rieger B, Namgaladze D, Herrera MG, Fiesel FC, Springer W, Mendes M, Stepien J, Barkovits K, Marcus K, Sickmann A, Dittmar G, Busch KB, Riedel D, Brini M, Tatzelt J, Cali T, Winklhofer KF. LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus. Embo j:e112006, 2022.
  • Zhang T, Künne C, Ding D, Günther S, Guo X, Zhou Y, Yuan X, Braun T. Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells. Nat Commun 13:6907, 2022.
  • Zhao H, Teng D, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca Di Magliano M, Boland GM, Flaherty KT, Swanson KD, Liu D, Rabinowitz JD, Zheng B. Myeloid-derived itaconate suppresses cytotoxic CD8(+) T cells and promotes tumour growth. Nat Metab, 2022.
  • Ainscough AJ, Smith TJ, Haensel M, Rhodes CJ, Fellows A, Whitwell HJ, Vasilaki E, Gray K, Freeman A, Howard LS, Wharton J, Dunmore B, Upton PD, Wilkins MR, Edel JB, Wojciak-Stothard B. An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis. Commun Biol 5:1192, 2022.
  • Drekolia MK, Talyan S, Cordellini Emídio R, Boon RA, Guenther S, Looso M, Dumbović G, Bibli SI. Unravelling the impact of aging on the human endothelial lncRNA transcriptome. Front Genet 13:1035380, 2022.
  • Koschade SE, Klann K, Shaid S, Vick B, Stratmann JA, Thölken M, Meyer LM, Nguyen TD, Campe J, Moser LM, Hock S, Baker F, Meyer CT, Wempe F, Serve H, Ullrich E, Jeremias I, Münch C, Brandts CH. Correction: Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia. Leukemia, 2022.
  • Rieth AJ, Rivinius R, Lühring T, Grün D, Keller T, Grinninger C, Schüttler D, Bara CL, Helmschrott M, Frey N, Sandhaus T, Schulze C, Kriechbaum S, Vietheer J, Sindermann J, Welp H, Lichtenberg A, Choi YH, Richter M, Tello K, Richter MJ, Hamm CW, Boeken U. Hemodynamic markers of pulmonary vasculopathy for prediction of early right heart failure and mortality after heart transplantation. J Heart Lung Transplant, 2022.
  • Chu X, Lingampally A, Moiseenko A, Kheirollahi V, Vazquez-Armendariz AI, Koepke J, Khadim A, Kiliaris G, Shahriari Felordi M, Zabihi M, Shalashova I, Alexopoulos I, Günther S, Lebrigand K, Truchi M, Günther A, Braun T, Mari B, Samakovlis C, Li X, Seeger W, Herold S, Zhang JS, Bellusci S, El Agha E. GLI1+ cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. Cell Mol Life Sci 79:581, 2022.
  • Leisegang MS, Bains JK, Seredinski S, Oo JA, Krause NM, Kuo CC, Günther S, Sentürk Cetin N, Warwick T, Cao C, Boos F, Izquierdo Ponce J, Haydar S, Bednarz R, Valasarajan C, Fuhrmann DC, Preussner J, Looso M, Pullamsetti SS, Schulz MH, Jonker HRA, Richter C, Rezende F, Gilsbach R, Pflüger-Müller B, Wittig I, Grummt I, Ribarska T, Costa IG, Schwalbe H, Brandes RP. HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nat Commun 13:6563, 2022.
  • Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, David Schmid C, Xi Y, Stojanovic A, Tonack S, De La Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S, Géraud C. Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression. Circulation, 2022.
  • Schwartz GG, Szarek M, Zeiher A, White HD, Jukema JW, Harrington RA, Goodman SG, Diaz R, Bittner V, Bhatt DL, Steg PG. Elevated C-Reactive Protein Amplifies Association of Lipoprotein(a) With Cardiovascular Risk and Clinical Benefit of Alirocumab. J Am Coll Cardiol, 2022. letter
  • Tjaden A, Giessmann RT, Knapp S, Schröder M, Müller S. High-content live-cell multiplex screen for chemogenomic compound annotation based on nuclear morphology. STAR Protoc 3:101791, 2022.
  • Voorneveld J, Kloet MS, Wijngaarden S, Kim RQ, Moutsiopoulou A, Verdegaal M, Misra M, Đikić I, Van Der Marel GA, Overkleeft HS, Filippov DV, Van Der Heden Van Noort GJ. Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins. J Am Chem Soc, 2022.
  • Wygrecka M, Wujak L, Markart P, Kosanovic D, Müller-Redetzky HC, Witzenrath M, Henneke I, Schermuly RT, Seeger W, Schaefer L, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Maat S, Maas C. Erratum: Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury. Am J Respir Crit Care Med 206:1184, 2022. Published erratum

New in PubMed in Archive