New this week in PubMed from CPI Institute

  • Arcari L, Engel J, Freiwald T, Zhou H, Zainal H, Gawor M, Buettner S, Geiger H, Hauser I, Nagel E, Puntmann VO. Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance. J Cardiovasc Magn Reson 23:71, 2021.
  • Burch AE, Erath JW, Kutyifa V, Aßmus B, Bonderman D, Russo AM. Decline in physical activity in the weeks preceding sustained ventricular arrhythmia in women. Heart Rhythm O2 1:283-287, 2020.
  • Malkomes P, Lunger I, Oppermann E, Abou-El-Ardat K, Oellerich T, Günther S, Canbulat C, Bothur S, Schnütgen F, Yu W, Wingert S, Haetscher N, Catapano C, Dietz MS, Heilemann M, Kvasnicka HM, Holzer K, Serve H, Bechstein WO, Rieger MA. Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53. Oncogene, 2021.
  • Rieth AJ, Richter MJ, Tello K, Gall H, Ghofrani HA, Guth S, Wiedenroth CB, Seeger W, Kriechbaum SD, Mitrovic V, Schulze PC, Hamm CW. Exercise hemodynamics in heart failure patients with preserved and mid-range ejection fraction: key role of the right heart. Clin Res Cardiol, 2021.
  • Schmidt SH, Weng JH, Aoto PC, Boassa D, Mathea S, Silletti S, Hu J, Wallbott M, Komives EA, Knapp S, Herberg FW, Taylor SS. Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2. Proc Natl Acad Sci U S A 118, 2021.
  • Sommer N, Weissmann N, Ghofrani HA. Metabolic Reprogramming in Congenital Cyanotic Heart Disease: Another Fight in Puberty? Circulation 143:2273-2276, 2021. editorial
  • Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schaffer A, Kur IM, Czlonka E, Wachtel C, Tsoukala I, Muller L, Schafer AL, Weitmann M, Dinse P, Alberto E, Buck MC, Landry JJM, Baying B, Slotta-Huspenina J, Roesler J, Harter PN, Kubasch AS, Meinel J, Elwakeel E, Strack E, Tran Quang C, Abdel-Wahab O, Schmitz M, Weigert A, Schmid T, Platzbecker U, Benes V, Ghysdael J, Bonig H, Gotze KS, Rothlin CV, Ghosh S, Medyouf H. AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia. Cancer Discov, 2021.
  • Amrhein JA, Knapp S, Hanke T. Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors. J Med Chem, 2021.
  • Chu X, Taghizadeh S, Vazquez-Armendariz AI, Herold S, Chong L, Chen C, Zhang JS, El Agha E, Bellusci S. Validation of a Novel Fgf10 (Cre-ERT2) Knock-in Mouse Line Targeting FGF10(Pos) Cells Postnatally. Front Cell Dev Biol 9:671841, 2021.
  • Fischer C, Wilken-Schmitz A, Hernandez-Olmos V, Proschak E, Stark H, Fleming I, Weigert A, Thurn M, Hofmann M, Werner ER, Geisslinger G, Niederberger E, Watschinger K, Tegeder I. AGMO Inhibitor Reduces 3T3-L1 Adipogenesis. Cells 10, 2021.
  • Gerçek M, Oldenburg O, Gerçek M, Fox H, Rudolph V, Puehler T, Omran H, Wolf LK, Hakim-Meibodi K, Zeiher AM, Gummert J, Dimitriadis Z. Prevalence of Sleep Disordered Breathing in Patients with Primary Mitral Regurgitation Undergoing Mitral Valve Surgery. J Clin Med 10, 2021.
  • Hecker M, Sommer N, Mayer K. Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation. Methods Mol Biol 2277:125-132, 2021.
  • Hofmann FJ, Dörr O, Blachutzik F, Boeder N, Elsässer A, Keranov S, Köhne A, Hofmann S, Möllmann H, Hamm C, Nef HM. Latest Developments in Robotic Percutaneous Coronary Intervention. Surg Technol Int 38, 2021.
  • Ianni A, Kumari P, Tarighi S, Argento FR, Fini E, Emmi G, Bettiol A, Braun T, Prisco D, Fiorillo C, Becatti M. An Insight into Giant Cell Arteritis Pathogenesis: Evidence for Oxidative Stress and SIRT1 Downregulation. Antioxidants (Basel) 10, 2021.
  • Lo HS, Hui KPY, Lai HM, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH, Ng KC, Ho JCW, Chen YW, Ma B, Cheung PM, Shin D, Wang K, Lee MH, Selisko B, Eydoux C, Guillemot JC, Canard B, Wu KP, Liang PH, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong KB, Mok CKP, Ko H, Aik WS, Chan MCW, Ng WL. Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir. ACS Cent Sci 7:792-802, 2021.
  • Maculins T, Verschueren E, Hinkle T, Choi M, Chang P, Chalouni C, Rao S, Kwon Y, Lim J, Katakam AK, Kunz RC, Erickson BK, Huang T, Tsai TH, Vitek O, Reichelt M, Senbabaoglu Y, Mckenzie B, Rohde JR, Dikic I, Kirkpatrick DS, Murthy A. Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response. Elife 10, 2021.
  • Meier JK, Schnetz M, Beck S, Schmid T, Dominguez M, Kalinovic S, Daiber A, Brüne B, Jung M. Iron-Bound Lipocalin-2 Protects Renal Cell Carcinoma from Ferroptosis. Metabolites 11, 2021.
  • Peguera B, Segarra M, Acker-Palmer A. Neurovascular crosstalk coordinates the central nervous system development. Curr Opin Neurobiol 69:202-213, 2021. review
  • Reynders M, Chaikuad A, Berger BT, Bauer K, Koch P, Laufer S, Knapp S, Trauner D. Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angew Chem Int Ed Engl, 2021.
  • Rimola V, Osthues T, Königs V, Geißlinger G, Sisignano M. Oxaliplatin Causes Transient Changes in TRPM8 Channel Activity. Int J Mol Sci 22, 2021.
  • Sommer N, Pak O, Hecker M. New Avenues for Anti-inflammatory Signaling of Nur77 in Acute Lung Injury. Am J Respir Cell Mol Biol, 2021.
  • Tesch R, Rak M, Raab M, Berger LM, Kronenberger T, Joerger AC, Berger BT, Abdi I, Hanke T, Poso A, Strebhardt K, Sanhaji M, Knapp S. Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. J Med Chem, 2021.
  • Yogeswaran A, Troidl C, Mcnamara JW, Wilhelm J, Truschel T, Widmann L, Aslam M, Hamm CW, Sadayappan S, Lipps C. The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling. Cells 10, 2021.

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