November 2020

  • Assmus B, Cremer S, Kirschbaum K, Culmann D, Kiefer K, Dorsheimer L, Rasper T, Abou-El-Ardat K, Herrmann E, Berkowitsch A, Hoffmann J, Seeger F, Mas-Peiro S, Rieger MA, Dimmeler S,Zeiher AM. Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations. Eur Heart J, 2020
  • Ebert P,Schulz MH. Fast detection of differential chromatin domains with SCIDDO. Bioinformatics, 2020.
  • Fischer-Rasokat U, Renker M, Liebetrau C, Möllmann H, Hamm CW,Kim WK. Impact of Rapid Ventricular Pacing During Transcatheter Implantation of Self-Expanding Aortic Valve Prostheses in Patients at Highest Risk. J Invasive Cardiol, 2020.
  • Guzik TJ,Dimmeler S. Leaders in Cardiovascular Research: Stefanie Dimmeler. Cardiovasc Res 116:e202-e204, 2020.
  • Husain-Syed F, Vadász I, Wilhelm J, Walmrath HD, Seeger W, Birk HW, Jennert B, Dietrich H, Herold S, Trauth J, Tello K, Sander M, Morty RE, Slanina H, Schüttler CG, Ziebuhr J, Kassoumeh S, Ronco C, Ferrari F, Warnatz K, Stahl K, Seeliger B, Hoeper MM, Welte T,David S. Immunoglobulin Deficiency as an Indicator of Disease Severity in Patients with COVID-19. Am J Physiol Lung Cell Mol Physiol, 2020.
  • Mamazhakypov A, Weiß A, Zukunft S, Sydykov A, Kojonazarov B, Wilhelm J, Vroom C, Petrovic A, Kosanovic D, Weissmann N, Seeger W, Fleming I, Iglarz M, Grimminger F, Ghofrani HA, Pullamsetti SS,Schermuly RT. Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats. Pulm Circ 10:2045894020947283, 2020.
  • Mostazo MGC, Kurrle N, Casado M, Fuhrmann D, Alshamleh I, Häupl B, Martín-Sanz P, Brüne B, Serve H, Schwalbe H, Schnütgen F, Marin S,Cascante M. Metabolic Plasticity Is an Essential Requirement of Acquired Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia. Cancers (Basel) 12, 2020.
  • Mukherjee D, Wagh G, Mokalled MH, Kontarakis Z, Dickson AL, Rayrikar A, Günther S, Poss KD, Stainier DYR,Patra C. Ccn2a/Ctgfa is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish. Development, 2020.
  • Nef HM, Elsässer A, Möllmann H, Abdel-Hadi M, Bauer T, Brück M, Eggebrecht H, Ehrlich JR, Ferrari MW, Fichtlscherer S, Hink U, Hölschermann H, Kacapor R, Koeth O, Korboukov S, Lamparter S, Laspoulas AJ, Lehmann R, Liebetrau C, Plücker T, Pons-Kühnemann J, Schächinger V, Schieffer B, Schott P, Schulze M, Teupe C, Vasa-Nicotera M, Weber M, Weinbrenner C, Werner G, Hamm CW,Dörr O. Impact of the COVID-19 pandemic on cardiovascular mortality and catherization activity during the lockdown in central Germany: an observational study. Clin Res Cardiol:1-10, 2020.
  • Risteski P, Radwan M, Boshkoski G, Salem R, Iavazzo A, Walther T,Esposito G. Minimally Invasive Aortic Arch Repair: Technical Considerations and Mid-Term Outcomes. Heart Surg Forum 23:E803-e808, 2020.
  • Risteski P, Salem R, Walther T, Kessel J,Bechstein WO. Homograft Treatment for Infected Frozen Elephant Trunk Prosthesis. Heart Surg Forum 23:E786-e788, 2020.
  • Schulz R, Andreadou I, Hausenloy DJ,Ferdinandy P. Risk factors, co-morbidities, and co-medications in cardioprotection: Importance for translation. Br J Pharmacol 177:5249-5251, 2020.
  • Abdel-Wahab M, Fujita B, Frerker C, Bauer T, Beckmann A, Bekeredjian R, Bleiziffer S, Möllmann H, Walther T, Hamm C, Beyersdorf F, Zeiher A, Gummert J, Herrmann E, Borger MA, Holzhey D, Thiele H Ensminger S. Transcatheter Versus Rapid-Deployment Aortic Valve Replacement: A Propensity-Matched Analysis From the German Aortic Valve Registry. JACC Cardiovasc Interv 13:2642-2654, 2020.
  • Cremer S, Jakob C, Berkowitsch A, Borgmann S, Pilgram L, Tometten L, Classen A, Wille K, Weidlich S, Gruener B, Dimmeler S, Massberg S, Rieg S Zeiher AM. Elevated markers of thrombo-inflammatory activation predict outcome in patients with cardiovascular comorbidities and COVID-19 disease: insights from the LEOSS registry. Clin Res Cardiol:1-12, 2020.
  • Guendel F, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Cheng HW, Heinz GA, Heinrich F, Durek P, Norris PS, Ware CF, Ruedl C, Herold S, Pfeffer K, Hehlgans T, Waisman A, Becher B, Giannou AD, Brachs S, Ebert K, Tanriver Y, Ludewig B, Mashreghi MF, Kruglov AA Diefenbach A. Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity 53:1015-1032.e8, 2020.
  • Lahm H, Jia M, Dreßen M, Wirth FFM, Puluca N, Gilsbach R, Keavney B, Cleuziou J, Beck N, Bondareva O, Dzilic E, Burri M, König KC, Ziegelmüller JA, Abou-Ajram C, Neb I, Zhang Z, Doppler SA, Mastantuono E, Lichtner P, Eckstein G, Hörer J, Ewert P, Priest JR, Hein L, Lange R, Meitinger T, Cordell HJ, Müller-Myhsok B Krane M. Congenital heart disease risk loci identified by genome-wide association study in European patients. J Clin Invest, 2020.
  • Lother A, Bondareva O, Saadatmand AR, Pollmeier L, Härdtner C, Hilgendorf I, Weichenhan D, Eckstein V, Plass C, Bode C, Backs J, Hein L Gilsbach R. Diabetes changes gene expression but not DNA methylation in cardiac cells. J Mol Cell Cardiol, 2020.
  • Picado A, Chaikuad A, Wells CI, Shrestha S, Zuercher WJ, Pickett JE, Kwarcinski FE, Sinha P, De Silva CS, Zutshi R, Liu S, Kannan N, Knapp S, Drewry DH Willson TM. A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. J Med Chem, 2020.
  • Priya R, Allanki S, Gentile A, Mansingh S, Uribe V, Maischein HM Stainier DYR. Tension heterogeneity directs form and fate to pattern the myocardial wall. Nature, 2020.
  • Ren H, Bakas NA, Vamos M, Chaikuad A, Limpert AS, Wimer CD, Brun SN, Lambert LJ, Tautz L, Celeridad M, Sheffler DJ, Knapp S, Shaw RJ Cosford NDP. Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer. J Med Chem, 2020
  • Taghizadeh S, Jones MR, Olmer R, Ulrich S, Danopoulos S, Shen C, Chen C, Wilhelm J, Martin U, Chen C, Al Alam D Bellusci S. Fgf10 Signaling-Based Evidence for the Existence of an Embryonic Stage Distinct From the Pseudoglandular Stage During Mouse Lung Development. Front Cell Dev Biol 8:576604, 2020.
  • Valina C, Neumann FJ, Menichelli M, Mayer K, Wöhrle J, Bernlochner I, Aytekin A, Richardt G, Witzenbichler B, Sibbing D, Cassese S, Angiolillo DJ, Kufner S, Liebetrau C, Hamm CW, Xhepa E, Hapfelmeier A, Sager HB, Wustrow I, Joner M, Trenk D, Laugwitz KL, Schunkert H, Schüpke S Kastrati A. Ticagrelor or Prasugrel in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. J Am Coll Cardiol 76:2436-2446, 2020.
  • Wanior M, Preuss F, Ni X, Krämer A, Mathea S, Göbel T, Heidenreich D, Simonyi S, Kahnt AS, Joerger AC Knapp S. Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J Med Chem, 2020.
  • Zemrak F, Raisi-Estabragh Z, Khanji MY, Mohiddin SA, Bruder O, Wagner A, Lombardi M, Schwitter J, Van Rossum AC, Pilz G, Nothnagel D, Steen H, Nagel E, Prasad SK, Deluigi CC, Dill T, Frank H, Schneider S, Mahrholdt H Petersen SE. Left Ventricular Hypertrabeculation Is Not Associated With Cardiovascular Morbity or Mortality: Insights From the Eurocmr Registry. Front Cardiovasc Med 7:158, 2020.
  • Chelladurai P, Savai R Pullamsetti SS. Zooming into Cellular and Molecular Heterogeneity of Pulmonary Hypertension: What More Single-cell Omics Can Offer. Am J Respir Crit Care Med, 2020.
  • Daiber A, Kuntic M, Hahad O, Delogu LG, Rohrbach S, Di Lisa F, Schulz R Münzel T. Effects of air pollution particles (ultrafine and fine particulate matter) on mitochondrial function and oxidative stress – Implications for cardiovascular and neurodegenerative diseases. Arch Biochem Biophys:108662, 2020.
  • Hiebel C, Stürner E, Hoffmeister M, Tascher G, Schwarz M, Nagel H, Behrends C, Münch C Behl C. BAG3 Proteomic Signature under Proteostasis Stress. Cells 9, 2020.
  • Kawashima H, Hara H, Wang R, Ono M, Gao C, Takahashi K, Suryapranata H, Walsh S, Cotton J, Carrie D, Sabate M, Steinwender C, Leibundgut G, Wykrzykowska J, Hamm C, Jüni P, Vranckx P, Valgimigli M, Windecker S, De Winter RJ, Sharif F, Onuma Y Serruys PW. Usefulness of updated logistic clinical SYNTAX score based on MI-SYNTAX score in patients with ST-elevation myocardial infarction. Catheter Cardiovasc Interv, 2020.
  • Keranov S, Dörr O, Jafari L, Troidl C, Liebetrau C, Kriechbaum S, Keller T, Voss S, Bauer T, Lorenz J, Richter MJ, Tello K, Gall H, Ghofrani HA, Mayer E, Wiedenroth CB, Guth S, Lörchner H, Pöling J, Chelladurai P, Pullamsetti SS, Braun T, Seeger W, Hamm CW Nef H. CILP1 as a biomarker for right ventricular maladaptation in pulmonary hypertension. Eur Respir J, 2020.
  • Rimola V, Hahnefeld L, Zhao J, Jiang C, Angioni C, Schreiber Y, Osthues T, Pierre S, Geisslinger G, Ji RR, Scholich K Sisignano M. Lysophospholipids contribute to oxaliplatin-induced acute peripheral pain. J Neurosci, 2020.
  • Snodgrass RG, Benatzy Y, Schmid T, Namgaladze D, Mainka M, Schebb NH, Lütjohann D Brüne B. Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation. Cell Death Differ, 2020.
  • Vadász I, Husain-Syed F, Dorfmüller P, Roller FC, Tello K, Hecker M, Morty RE, Gattenlöhner S, Walmrath HD, Grimminger F, Herold S Seeger W. Severe organising pneumonia following COVID-19. Thorax, 2020.
  • Wolf A, Kutsche HS, Schreckenberg R, Weber M, Li L, Rohrbach S, Schulz R Schlüter KD. Autocrine effects of PCSK9 on cardiomyocytes. Basic Res Cardiol 115:65, 2020.
  • Abplanalp WT, Cremer S, John D, Hoffmann J, Schuhmacher B, Merten M, Rieger MA, Vasa-Nicotera M, Zeiher AM Dimmeler S. Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure. Circ Res, 2020
  • Bojkova D, Bechtel M, Mclaughlin KM, Mcgreig JE, Klann K, Bellinghausen C, Rohde G, Jonigk D, Braubach P, Ciesek S, Münch C, Wass MN, Michaelis M Cinatl J, Jr. Aprotinin Inhibits SARS-CoV-2 Replication. Cells 9, 2020
  • Grigoratos C, Gueli I, Arendt CT, Leithner D, Meloni A, Nugara C, Barison A, Todiere G, Puntmann VO, Novo G, Pepe A, Emdin M, Nagel E, Aquaro GD. Prevalence and prognostic impact of nonischemic late gadolinium enhancement in stress cardiac magnetic resonance. J Cardiovasc Med (Hagerstown) 21:980-985, 2020
  • Kyselova A, Siragusa M, Anthes J, Solari FA, Loroch S, Zahedi RP, Walter U, Fleming I, Randriamboavonjy V. Cyclin Y is expressed in Platelets and Modulates Integrin Outside-in Signaling. Int J Mol Sci 21, 2020
  • Oo JA, Irmer B, Günther S, Warwick T, Pálfi K, Izquierdo Ponce J, Teichmann T, Pflüger-Müller B, Gilsbach R, Brandes RP Leisegang MS. ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting. Sci Rep 10:19079, 2020
  • Pullamsetti SS, Nayakanti S, Chelladurai P, Mamazhakypov A, Mansouri S, Savai R Seeger W. Cancer and pulmonary hypertension: Learning lessons and real-life interplay. Glob Cardiol Sci Pract 2020:e202010, 2020.