December 2023

• Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M. RSV vaccination strategies for high-risk patients 2023: a collaborative position paper by leading German medical societies and organizations. Infection, 2023.

• Boyer L, Zebachi S, Gallien S, Margarit L, Ribeiro Baptista B, Lopez-Zaragoza JL, D’humières T, Zerah F, Hue S, Derumeaux G, Adnot S, Audureau E, Lelièvre JD. Combined effects of smoking and HIV infection on the occurrence of aging-related manifestations. Sci Rep 13:21745, 2023.

• Dönig J, Mende H, Davila Gallesio J, Wagner K, Hotz P, Schunck K, Piller T, Hölper S, Uhan S, Kaulich M, Wirth M, Keller U, Tascher G, Bohnsack KE, Müller S. Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis. Nat Commun 14:8121, 2023.

• Enssle JC, Campe J, Moter A, Voit I, Gessner A, Yu W, Wolf S, Steffen B, Serve H, Bremm M, Huenecke S, Lohoff M, Vehreschild M, Rabenau HF, Widera M, Ciesek S, Oellerich T, Imkeller K, Rieger MA, Von Metzler I, Ullrich E. Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients. Leukemia, 2023.

• Jakwerth CA, Weckmann M, Illi S, Charles H, Zissler UM, Oelsner M, Guerth F, Omony J, Nemani SSP, Grychtol R, Dittrich AM, Skevaki C, Foth S, Weber S, Alejandre Alcazar MA, Van Koningsbruggen-Rietschel S, Brock R, Blau S, Hansen G, Bahmer T, Rabe KF, Brinkmann F, Kopp MV, Chaker AM, Schaub B, Von Mutius E, Schmidt-Weber CB. 17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma. Am J Respir Crit Care Med, 2023.

• Kim WK, Eckel C, Charitos EI, Renker M, Grothusen C, Choi YH, Hamm C, Blumenstein J, Sossalla S, Möllmann H. Risk Assessment of Coronary Obstruction for the Acurate Transcatheter Heart Valve. Am J Cardiol, 2023.

• Kurian L, Brandes RP. RNA Modification That Breaks the Heart: RNA Acetylase Nat10 Promotes Fibrosis. Circ Res 133:1003-1005, 2023.

• Lindberg MF, Deau E, Miege F, Greverie M, Roche D, George N, George P, Merlet L, Gavard J, Brugman SJT, Aret E, Tinnemans P, De Gelder R, Sadownik J, Verhofstad E, Sleegers D, Santangelo S, Dairou J, Fernandez-Blanco Á, Dierssen M, Krämer A, Knapp S, Meijer L. Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer’s Disease Drug Candidate. J Med Chem, 2023.

• Outhwaite IR, Singh S, Berger BT, Knapp S, Chodera JD, Seeliger MA. Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting. Elife 12, 2023.

• Qian X, Klatt S, Bennewitz K, Wohlfart DP, Lou B, Meng Y, Buettner M, Poschet G, Morgenstern J, Fleming T, Sticht C, Hausser I, Fleming I, Szendroedi J, Nawroth PP, Kroll J. Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease. Adv Sci (Weinh):e2302325, 2023.

• Trif C, Banica AM, Manolache A, Anghel SA, Huţanu DE, Stratulat T, Badea R, Oprita G, Selescu T, Petrescu SM, Sisignano M, Offermanns S, Babes A, Tunaru S. Inhibition of TRPM8 function by the prostacyclin receptor requires coupling to Gq/11 proteins. Br J Pharmacol, 2023.

• Kattih B, Boeckling F, Shumliakivska M, Tombor L, Rasper T, Schmitz K, Hoffmann J, Nicin L, Abplanalp WT, Carstens DC, Arsalan M, Emrich F, Holubec T, Walther T, Puntmann VO, Nagel E, John D, Zeiher AM, Dimmeler S. Single-nuclear transcriptome profiling identifies persistent fibroblast activation in hypertrophic and failing human hearts of patients with longstanding disease. Cardiovasc Res 119:2550-2562, 2023.

• Bonnavion R, Liu S, Kawase H, Roquid KA, Offermanns S. Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5). Front Pharmacol 14:1297596, 2023.González A, Dikić I. Decoding Golgiphagy: selective recycling under stress. Cell Res, 2023.

• Sanz Murillo M, Villagran Suarez A, Dederer V, Chatterjee D, Alegrio Louro J, Knapp S, Mathea S, Leschziner AE. Inhibition of Parkinson’s disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Sci Adv 9:eadk6191, 2023.

• Smadja DM, Philippe A, Ferreira EVM, Oliveira RKF, Mccabe C, Zhao L. CD147 Plasma Levels in Hospitalised Patients with Covid-19 Pneumonia Predict Illness Severity and In-Hospital Mortality. Stem Cell Rev Rep, 2023.

• Tiek D, Wells CI, Schröder M, Song X, Alamillo-Ferrer C, Goenka A, Iglesia R, Lu M, Hu B, Kwarcinski F, Sintha P, De Silva C, Hossain MA, Picado A, Zuercher W, Zutshi R, Knapp S, Riggins RB, Cheng SY, Drewry DH. SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Curr Res Chem Biol 3, 2023.

• Walters R, Vasilaki E, Wilkins MR, Zhao L, Rhodes CJ. Response by Walters et al to Letter Regarding Article, “SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension“. Circulation 148:1825-1826, 2023. letter