March 2022

cAli WB, Ludwig S, Duncan A, Weimann J, Nickenig G, Tanaka T, Coisne A, Vincentelli A, Makkar R, Webb JG, Akodad M, Muller DWM, Praz F, Wild MG, Hausleiter J, Goel SS, Von Ballmoos MW, Denti P, Chehab O, Redwood S, Dahle G, Baldus S, Adam M, Ruge H, Lange R, Kaneko T, Leroux L, Dumonteil N, Tchetche D, Treede H, Flagiello M, Obadia JF, Walther T, Taramasso M, Søndergaard L, Bleiziffer S, Rudolph TK, Fam N, Kempfert J, Granada JF, Tang GHL, Von Bardeleben RS, Conradi L, Modine T. Characteristics and Outcomes of Patients Screened for Transcatheter Mitral Valve Implantation: 1-Year Results from the CHOICE-MI Registry. Eur J Heart Fail, 2022.
Aslam M, Idrees H, Ferdinandy P, Helyes Z, Hamm C, Schulz R. Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro. Int J Mol Sci 23, 2022.
Birnhuber A, Jandl K, Biasin V, Fließer E, Valzano F, Marsh LM, Krolczik C, Olschewski A, Wilhelm J, Toller W, Heinemann A, Olschewski H, Wygrecka M, Kwapiszewska G. Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of SSc-ILD. Eur Respir J, 2022.
Coxam B, Collins RT, Hußmann M, Huisman Y, Meier K, Jung S, Bartels-Klein E, Szymborska A, Finotto L, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H. Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. Development 149, 2022.
Dimitrov T, Anli C, Moschopoulou AA, Kronenberger T, Kudolo M, Geibel C, Schwalm MP, Knapp S, Zender L, Forster M, Laufer S. Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity. Eur J Med Chem 235:114234, 2022.
Glueck M, Koch A, Brunkhorst R, Ferreiros Bouzas N, Trautmann S, Schaefer L, Pfeilschifter W, Pfeilschifter J, Vutukuri R. The atypical sphingosine 1-phosphate variant, d16:1 S1P, mediates CTGF induction via S1P2 activation in renal cell carcinoma. Febs j, 2022.
Jones RJ, De Bie E, Groves E, Zalewska KI, Swietlik EM, Treacy CM, Martin JM, Polwarth G, Li W, Guo J, Baxendale HE, Coleman S, Savinykh N, Coghlan JG, Corris PA, Howard LS, Johnson MK, Church C, Kiely DG, Lawrie A, Lordan JL, Mackenzie Ross RV, Pepke Zaba J, Wilkins MR, Wort SJ, Fiorillo E, Orrù V, Cucca F, Rhodes CJ, Gräf S, Morrell NW, Mckinney EF, Wallace C, Toshner M. Autoimmunity is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med, 2022.
Pandi-Perumal SR, Kumar VM, Pandian NG, De Jong JT, Andiappan S, Corlateanu A, Mahalaksmi AM, Chidambaram SB, Kumar RR, Ramasubramanian C, Sivasubramaniam S, Bjørkum AA, Cutajar J, Berk M, Trakht I, Vrdoljak A, Meira ECM, Eyre HA, Grønli J, Cardinali DP, Maercker A, Van De Put W, Guzder J, Bjorvatn B, Tol WA, Acuña-Castroviejo D, Meudec M, Morin CM, Partinen M, Barbui C, Jordans MJD, Braakman MH, Knaevelsrud C, Pallesen S, Sijbrandij M, Golombek DA, Espie CA, Cuijpers P, Agudelo HaM, Van Der Velden K, Van Der Kolk BA, Hobfoll SE, Devillé W, Gradisar M, Riemann D, Axelsson J, Benítez-King G, Macy RD, Poberezhets V, Hoole SRH, Murthy RS, Hegemann T, Heinz A, Salvage J, Mcfarlane AC, Keukens R, De Silva H, Oestereich C, Wilhelm J, Von Cranach M, Hoffmann K, Klosinski M, Bhugra D, Seeman MV. Scientists Against War: A Plea to World Leaders for Better Governance. Sleep Vigil:1-6, 2022. editorial
Raue R, Frank AC, Fuhrmann DC, De La Cruz-Ojeda P, Rösser S, Bauer R, Cardamone G, Weigert A, Syed SN, Schmid T, Brüne B. MicroRNA-200c Attenuates the Tumor-Infiltrating Capacity of Macrophages. Biology (Basel) 11, 2022.
Schebb NH, Kühn H, Kahnt AS, Rund KM, O’donnell VB, Flamand N, Peters-Golden M, Jakobsson PJ, Weylandt KH, Rohwer N, Murphy RC, Geisslinger G, Fitzgerald GA, Hanson J, Dahlgren C, Alnouri MW, Offermanns S, Steinhilber D. Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? Front Pharmacol 13:838782, 2022. review
Schofer N, Jeschke E, Kröger J, Baberg H, Falk V, Gummert JF, Hamm CW, Möckel M, Goßling A, Malzahn J, Günster C, Blankenberg S. Risk-related short-term clinical outcomes after transcatheter aortic valve implantation and their impact on early mortality: an analysis of claims-based data from Germany. Clin Res Cardiol, 2022.
Schramm F, Schaefer L, Wygrecka M. EGFR Signaling in Lung Fibrosis. Cells 11, 2022. review
Warwick T, Schulz MH, Gilsbach R, Brandes RP, Seuter S. Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Nucleic Acids Res, 2022.
Zisiopoulou M, Berkowitsch A, Neuber R, Gouveris H, Fichtlscherer S, Walther T, Vasa-Nicotera M, Seppelt P. Personalized Preoperative Prediction of the Length of Hospital Stay after TAVI Using a Dedicated Decision Tree Algorithm. J Pers Med 12, 2022.
Hedström E, Ishida M, Sepúlveda-Martínez A, Ryd D, Sperling J, Engblom H, Nagel E. Correction to: The effect of initial teaching on evaluation of left ventricular volumes by cardiovascular magnetic resonance imaging: comparison between complete and intermediate beginners and experienced observers. BMC Med Imaging 22:41, 2022. Published erratum
Herrmann E, Huisl P, Aßmus B. [Novel European Heart Failure Guidelines – Change in Treatment Paradigms]. Dtsch Med Wochenschr 147:326-331, 2022.
Kolentinis M, Carerj LM, Vidalakis E, Giokoglu E, Martin S, Arendt C, Vogl TJ, Nagel E, Puntmann VO. Determination of scar area using native and post-contrast T1 mapping: Agreement with late gadolinium enhancement. Eur J Radiol 150:110242, 2022.
Schmitz ML, Dreute J, Pfisterer M, Günther S, Kracht M, Chillappagari S. SIAH ubiquitin E3 ligases as modulators of inflammatory gene expression. Heliyon 8:e09029, 2022.
Valasarajan C, Karger A, Savai R, Pullamsetti SS. LncRNAs: Emerging Regulators of PDGF Signaling. Am J Respir Cell Mol Biol, 2022.
Zarkesh I, Kazemi Ashtiani M, Shiri Z, Aran S, Braun T, Baharvand H. Synthetic developmental biology: Engineering approaches to guide multicellular organization. Stem Cell Reports, 2022. review
Abplanalp WT, Tucker N, Dimmeler S. Single-cell technologies to decipher cardiovascular diseases. Eur Heart J, 2022.
Brandes RP, Gründer S. Europhysiology 2022: bringing together the physiologists of Europe and the World : 16-18 September 2022, Tivoli Congress Center, Copenhagen, Denmark” as subtitle. Pflugers Arch:1-2, 2022. editorial
Drews F, Salhab A, Karunanithi S, Cheaib M, Jung M, Schulz M, Simon M. Broad domains of histone marks in the highly compact Paramecium macronuclear genome. Genome Res, 2022.
El-Sammak H, Yang B, Guenther S, Chen W, Marín-Juez R, Stainier DYR. A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. Circ Res:Circresaha121319929, 2022.
Gierhardt M, Pak O, Sydykov A, Kraut S, Schäffer J, Garcia C, Veith C, Zeidan EM, Brosien M, Quanz K, Esfandiary A, Saraji A, Hadzic S, Kojonazarov B, Wilhelm J, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Herden C, Schulz R, Weissmann N, Heger J, Sommer N. Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovasc Res 118:305-315, 2022.
Jayavelu AK, Wolf S, Buettner F, Alexe G, Häupl B, Comoglio F, Schneider C, Doebele C, Fuhrmann DC, Wagner S, Donato E, Andresen C, Wilke AC, Zindel A, Jahn D, Splettstoesser B, Plessmann U, Münch S, Abou-El-Ardat K, Makowka P, Acker F, Enssle JC, Cremer A, Schnütgen F, Kurrle N, Chapuy B, Löber J, Hartmann S, Wild PJ, Wittig I, Hübschmann D, Kaderali L, Cox J, Brüne B, Röllig C, Thiede C, Steffen B, Bornhäuser M, Trumpp A, Urlaub H, Stegmaier K, Serve H, Mann M, Oellerich T. The proteogenomic subtypes of acute myeloid leukemia. Cancer Cell, 2022.
Krybus M, Sieradzki M, Fahimi E, Metry S, Nüsing R, Geisslinger G, Steiner I, Daldrup T, Lehr M, Kojda G. Contribution of cyclooxygenase-1-dependent prostacyclin synthesis to bradykinin-induced dermal extravasation. Biomed Pharmacother 148:112786, 2022.
Ono M, Hara H, Kawashima H, Gao C, Wang R, Wykrzykowska JJ, Piek JJ, Garg S, Hamm C, Steg PG, Valgimigli M, Windecker S, Vranckx P, Onuma Y, Serruys PW. Ticagrelor monotherapy versus aspirin monotherapy at 12 months after percutaneous coronary intervention: a landmark analysis of the GLOBAL LEADERS trial. EuroIntervention, 2022.Pliquett RU, Brandes RP. Experimental uninephrectomy associates with less parasympathetic modulation of heart rate and facilitates sodium-dependent arterial hypertension. PLoS One 17:e0265086, 2022.
Rangwala AM, Berger BT, Robers MB, Knapp S, Seeliger MA. Resistance to kinase inhibition through shortened target engagement. Mol Cell Oncol 9:2029999, 2022.
Sisignano M, Gribbon P, Geisslinger G. Drug Repurposing to Target Neuroinflammation and Sensory Neuron-Dependent Pain. Drugs:1-17, 2022.
Störk S, Bernhardt A, Böhm M, Brachmann J, Dagres N, Frantz S, Hindricks G, Köhler F, Zeymer U, Rosenkranz S, Angermann C, Aßmus B. Pulmonary artery sensor system pressure monitoring to improve heart failure outcomes (PASSPORT-HF): rationale and design of the PASSPORT-HF multicenter randomized clinical trial. Clin Res Cardiol:1-11, 2022.
Bonagas N, Gustafsson NMS, Henriksson M, Marttila P, Gustafsson R, Wiita E, Borhade S, Green AC, Vallin KSA, Sarno A, Svensson R, Göktürk C, Pham T, Jemth AS, Loseva O, Cookson V, Kiweler N, Sandberg L, Rasti A, Unterlass JE, Haraldsson M, Andersson Y, Scaletti ER, Bengtsson C, Paulin CBJ, Sanjiv K, Abdurakhmanov E, Pudelko L, Kunz B, Desroses M, Iliev P, Färnegårdh K, Krämer A, Garg N, Michel M, Häggblad S, Jarvius M, Kalderén C, Jensen AB, Almlöf I, Karsten S, Zhang SM, Häggblad M, Eriksson A, Liu J, Glinghammar B, Nekhotiaeva N, Klingegård F, Koolmeister T, Martens U, Llona-Minguez S, Moulson R, Nordström H, Parrow V, Dahllund L, Sjöberg B, Vargas IL, Vo DD, Wannberg J, Knapp S, Krokan HE, Arvidsson PI, Scobie M, Meiser J, Stenmark P, Berglund UW, Homan EJ, Helleday T. Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress. Nat Cancer 3:156-172, 2022.
Briquet M, Rocher AB, Alessandri M, Rosenberg N, De Castro Abrantes H, Wellbourne-Wood J, Schmuziger C, Ginet V, Puyal J, Pralong E, Daniel RT, Offermanns S, Chatton JY. Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. J Cereb Blood Flow Metab:271678×221080324, 2022.
Gragnano F, Zwahlen M, Vranckx P, Heg D, Schmidlin K, Hamm C, Steg PG, Gargiulo G, Mcfadden EP, Onuma Y, Chichareon P, Benit E, Möllmann H, Janssens L, Leonardi S, Zurakowski A, Arrivi A, Van Geuns RJ, Huber K, Slagboom T, Calabrò P, Serruys PW, Jüni P, Valgimigli M, Windecker S. Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation: Per-Protocol Analysis of the GLOBAL LEADERS Trial. J Am Heart Assoc:e024291, 2022.
Holubec T, Rashid H, Hecker F, Karimian-Tabrizi A, Miskovic A, Hlavicka J, Zacek P, Van Linden A, Moritz A, Walther T. Early- and longer-term outcomes of David versus Florida sleeve procedure: propensity-matched comparison. Eur J Cardiothorac Surg, 2022.
Kattih B, Carstens DC, Boeckling F, Rasper T, Pergola G, Dimmeler S, Vasa-Nicotera M, Zeiher AM, Mas-Peiro S. Low Circulating Musclin is Associated With Adverse Prognosis in Patients Undergoing Transcatheter Aortic Valve Implantation at Low-Intermediate Risk. J Am Heart Assoc:e022792, 2022.
Keshavarz M, Faraj Tabrizi S, Ruppert AL, Pfeil U, Schreiber Y, Klein J, Brandenburger I, Lochnit G, Bhushan S, Perniss A, Deckmann K, Hartmann P, Meiners M, Mermer P, Rafiq A, Winterberg S, Papadakis T, Thomas D, Angioni C, Oberwinkler J, Chubanov V, Gudermann T, Gärtner U, Offermanns S, Schütz B, Kummer W. Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. Sci Immunol 7:eabf6734, 2022.
Qi J, Rittershaus A, Priya R, Mansingh S, Stainier DYR, Helker CSM. Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish. Elife 11, 2022.
Seredinski S, Boos F, Günther S, Oo JA, Warwick T, Izquierdo Ponce J, Lillich FF, Proschak E, Knapp S, Gilsbach R, Pflüger-Müller B, Brandes RP, Leisegang MS. DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. Mol Ther Nucleic Acids 27:1023-1035, 2022.
Singh RK, Soliman A, Guaitoli G, Störmer E, Von Zweydorf F, Dal Maso T, Oun A, Van Rillaer L, Schmidt SH, Chatterjee D, David JA, Pardon E, Schwartz TU, Knapp S, Kennedy EJ, Steyaert J, Herberg FW, Kortholt A, Gloeckner CJ, Versées W. Nanobodies as allosteric modulators of Parkinson’s disease-associated LRRK2. Proc Natl Acad Sci U S A 119, 2022.
Werner F, Kojonazarov B, Gaßner B, Abeßer M, Schuh K, Völker K, Baba HA, Dahal BK, Schermuly RT, Kuhn M. Correction to: Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice. Basic Res Cardiol 117:7, 2022. Published erratum

March 2022

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