June 2021

Brandes RP, Rezende F. Glycolysis and Inflammation: Partners in Crime! Circ Res.129:30-32, 2021. editorial
Fink C, Baal N, Wilhelm J, Sarode P, Weigel R, Schumacher V, Nettersheim D, Schorle H, Schröck C, Bergmann M, Kliesch S, Kressin M, Savai R. On the origin of germ cell neoplasia in situ: Dedifferentiation of human adult Sertoli cells in cross talk with seminoma cells in vitro. Neoplasia.23:731-742, 2021.
Frank AC, Raue R, Fuhrmann DC, Sirait-Fischer E, Reuse C, Weigert A, Lütjohann D, Hiller K, Syed SN, Brüne B. Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment. Theranostics.11:7570-7588, 2021.
Gentile A, Bensimon-Brito A, Priya R, Maischein HM, Piesker J, Guenther S, Gunawan F, Stainier DY. The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression. Elife.10, 2021.
Gunawan F, Priya R, Stainier DYR. Sculpting the heart: Cellular mechanisms shaping valves and trabeculae. Curr Opin Cell Biol.73:26-34, 2021. review
Körtel N, Rücklé C, Zhou Y, Busch A, Hoch-Kraft P, Sutandy FXR, Haase J, Pradhan M, Musheev M, Ostareck D, Ostareck-Lederer A, Dieterich C, Hüttelmaier S, Niehrs C, Rausch O, Dominissini D, König J, Zarnack K. Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning. Nucleic Acids Res. 2021.
Stone OA, Zhou B, Red-Horse K, Stainier DYR. Endothelial ontogeny and the establishment of vascular heterogeneity. Bioessays.43:e2100036, 2021.
Vazquez-Armendariz AI, Seeger W, Herold S, El Agha E. Protocol for the generation of murine bronchiolospheres. STAR Protoc.2:100594, 2021.
Zhu N, Swietlik EM, Welch CL, Pauciulo MW, Hagen JJ, Zhou X, Guo Y, Karten J, Pandya D, Tilly T, Lutz KA, Martin JM, Treacy CM, Rosenzweig EB, Krishnan U, Coleman AW, Gonzaga-Jauregui C, Lawrie A, Trembath RC, Wilkins MR, Morrell NW, Shen Y, Gräf S, Nichols WC, Chung WK. Correction to: Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Med.13:106, 2021.
Boeder NF, Kastner J, Mehilli J, Münzel T, Naber C, Neumann T, Richardt G, Schmermund A, Wöhrle J, Zahn R, Riemer T, Achenbach S, Hamm CW, Nef HM. Predictors of scaffold failure and impact of optimized scaffold implantation technique on outcome: Results from the German-Austrian ABSORB RegIstRy. Catheter Cardiovasc Interv, 2021.
Faudone G, Bischoff-Kont I, Rachor L, Willems S, Zhubi R, Kaiser A, Chaikuad A, Knapp S, Fürst R, Heering J, Merk D. Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells. J Med Chem, 2021.
Fischer-Rasokat U, Renker M, Liebetrau C, Weferling M, Rolf A, Doss M, Hamm CW, Kim WK. Prognostic impact of echocardiographic mean transvalvular gradients in patients with aortic stenosis and low flow undergoing transcatheter aortic valve implantation. Catheter Cardiovasc Interv, 2021.
Ianni A, Hofmann M, Kumari P, Tarighi S, Al-Tamari HM, Görgens A, Giebel B, Nolte H, Krüger M, Salwig I, Pullamsetti SS, Günther A, Schneider A, Braun T. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway. Front Cell Dev Biol 9:639162, 2021.
Onódi Z, Ruppert M, Kucsera D, Sayour AA, Tóth VE, Koncsos G, Novák J, Brenner GB, Makkos A, Baranyai T, Giricz Z, Görbe A, Leszek P, Gyöngyösi M, Horváth IG, Schulz R, Merkely B, Ferdinandy P, Radovits T, Varga ZV. AIM2-driven inflammasome activation in heart failure. Cardiovasc Res, 2021.
Pesce M, Agostoni P, Bøtker HE, Brundel B, Davidson SM, De Caterina R, Ferdinandy P, Girao H, Gyöngyösi M, Hulot JS, Lecour S, Perrino C, Schulz R, Sluijter JPG, Steffens S, Tancevski I, Gollmann-Tepeköylü C, Tschöpe C, Van Linthout S, Madonna R. COVID-19 related cardiac complications – from clinical evidences to basic mechanisms. Opinion paper of the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res, 2021.
Renker M, Baumann S, Hamm CW, Tesche C, Kim WK, Savage RH, Coenen A, Nieman K, De Geer J, Persson A, Kruk M, Kepka C, Yang DH, Schoepf UJ. Influence of coronary stenosis location on diagnostic performance of machine learning-based fractional flow reserve from CT angiography. J Cardiovasc Comput Tomogr, 2021.
Schulz M, Diehl V, Trebicka J, Wygrecka M, Schaefer L. Biglycan in hepatorenal crosstalk Biglycan: a regulator of hepatorenal inflammation and autophagy. Matrix Biol, 2021.
Tröbs M, Achenbach S, Nef HM, Gori T, Naber C, Neumann T, Richardt G, Schmermund A, Wöhrle J, Zahn R, Hamm CW. Everolimus eluting bioresorbable vascular scaffolds in patients with acute coronary syndromes: Two-year results from the German-Austrian ABSORB registry. Catheter Cardiovasc Interv, 2021.
Weferling M, Liebetrau C, Renker M, Fischer-Rasokat U, Choi YH, Hamm CW, Kim WK. Right bundle branch block is not associated with worse short- and mid-term outcome after transcatheter aortic valve implantation. PLoS One 16:e0253332, 2021.

Arcari L, Engel J, Freiwald T, Zhou H, Zainal H, Gawor M, Buettner S, Geiger H, Hauser I, Nagel E, Puntmann VO. Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance. J Cardiovasc Magn Reson 23:71, 2021.
Burch AE, Erath JW, Kutyifa V, Aßmus B, Bonderman D, Russo AM. Decline in physical activity in the weeks preceding sustained ventricular arrhythmia in women. Heart Rhythm O2 1:283-287, 2020.
Malkomes P, Lunger I, Oppermann E, Abou-El-Ardat K, Oellerich T, Günther S, Canbulat C, Bothur S, Schnütgen F, Yu W, Wingert S, Haetscher N, Catapano C, Dietz MS, Heilemann M, Kvasnicka HM, Holzer K, Serve H, Bechstein WO, Rieger MA. Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53. Oncogene, 2021.
Rieth AJ, Richter MJ, Tello K, Gall H, Ghofrani HA, Guth S, Wiedenroth CB, Seeger W, Kriechbaum SD, Mitrovic V, Schulze PC, Hamm CW. Exercise hemodynamics in heart failure patients with preserved and mid-range ejection fraction: key role of the right heart. Clin Res Cardiol, 2021.
Schmidt SH, Weng JH, Aoto PC, Boassa D, Mathea S, Silletti S, Hu J, Wallbott M, Komives EA, Knapp S, Herberg FW, Taylor SS. Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2. Proc Natl Acad Sci U S A 118, 2021.
Sommer N, Weissmann N, Ghofrani HA. Metabolic Reprogramming in Congenital Cyanotic Heart Disease: Another Fight in Puberty? Circulation 143:2273-2276, 2021. editorial
Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schaffer A, Kur IM, Czlonka E, Wachtel C, Tsoukala I, Muller L, Schafer AL, Weitmann M, Dinse P, Alberto E, Buck MC, Landry JJM, Baying B, Slotta-Huspenina J, Roesler J, Harter PN, Kubasch AS, Meinel J, Elwakeel E, Strack E, Tran Quang C, Abdel-Wahab O, Schmitz M, Weigert A, Schmid T, Platzbecker U, Benes V, Ghysdael J, Bonig H, Gotze KS, Rothlin CV, Ghosh S, Medyouf H. AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia. Cancer Discov, 2021.
Amrhein JA, Knapp S, Hanke T. Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors. J Med Chem, 2021.
Chu X, Taghizadeh S, Vazquez-Armendariz AI, Herold S, Chong L, Chen C, Zhang JS, El Agha E, Bellusci S. Validation of a Novel Fgf10 (Cre-ERT2) Knock-in Mouse Line Targeting FGF10(Pos) Cells Postnatally. Front Cell Dev Biol 9:671841, 2021.
Fischer C, Wilken-Schmitz A, Hernandez-Olmos V, Proschak E, Stark H, Fleming I, Weigert A, Thurn M, Hofmann M, Werner ER, Geisslinger G, Niederberger E, Watschinger K, Tegeder I. AGMO Inhibitor Reduces 3T3-L1 Adipogenesis. Cells 10, 2021.
Gerçek M, Oldenburg O, Gerçek M, Fox H, Rudolph V, Puehler T, Omran H, Wolf LK, Hakim-Meibodi K, Zeiher AM, Gummert J, Dimitriadis Z. Prevalence of Sleep Disordered Breathing in Patients with Primary Mitral Regurgitation Undergoing Mitral Valve Surgery. J Clin Med 10, 2021.
Hecker M, Sommer N, Mayer K. Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation. Methods Mol Biol 2277:125-132, 2021.
Hofmann FJ, Dörr O, Blachutzik F, Boeder N, Elsässer A, Keranov S, Köhne A, Hofmann S, Möllmann H, Hamm C, Nef HM. Latest Developments in Robotic Percutaneous Coronary Intervention. Surg Technol Int 38, 2021.
Ianni A, Kumari P, Tarighi S, Argento FR, Fini E, Emmi G, Bettiol A, Braun T, Prisco D, Fiorillo C, Becatti M. An Insight into Giant Cell Arteritis Pathogenesis: Evidence for Oxidative Stress and SIRT1 Downregulation. Antioxidants (Basel) 10, 2021.
Lo HS, Hui KPY, Lai HM, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH, Ng KC, Ho JCW, Chen YW, Ma B, Cheung PM, Shin D, Wang K, Lee MH, Selisko B, Eydoux C, Guillemot JC, Canard B, Wu KP, Liang PH, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong KB, Mok CKP, Ko H, Aik WS, Chan MCW, Ng WL. Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir. ACS Cent Sci 7:792-802, 2021.
Maculins T, Verschueren E, Hinkle T, Choi M, Chang P, Chalouni C, Rao S, Kwon Y, Lim J, Katakam AK, Kunz RC, Erickson BK, Huang T, Tsai TH, Vitek O, Reichelt M, Senbabaoglu Y, Mckenzie B, Rohde JR, Dikic I, Kirkpatrick DS, Murthy A. Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response. Elife 10, 2021.
Meier JK, Schnetz M, Beck S, Schmid T, Dominguez M, Kalinovic S, Daiber A, Brüne B, Jung M. Iron-Bound Lipocalin-2 Protects Renal Cell Carcinoma from Ferroptosis. Metabolites 11, 2021.
Peguera B, Segarra M, Acker-Palmer A. Neurovascular crosstalk coordinates the central nervous system development. Curr Opin Neurobiol 69:202-213, 2021. review
Reynders M, Chaikuad A, Berger BT, Bauer K, Koch P, Laufer S, Knapp S, Trauner D. Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angew Chem Int Ed Engl, 2021.
Rimola V, Osthues T, Königs V, Geißlinger G, Sisignano M. Oxaliplatin Causes Transient Changes in TRPM8 Channel Activity. Int J Mol Sci 22, 2021.
Sommer N, Pak O, Hecker M. New Avenues for Anti-inflammatory Signaling of Nur77 in Acute Lung Injury. Am J Respir Cell Mol Biol, 2021.
Tesch R, Rak M, Raab M, Berger LM, Kronenberger T, Joerger AC, Berger BT, Abdi I, Hanke T, Poso A, Strebhardt K, Sanhaji M, Knapp S. Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. J Med Chem, 2021.
Yogeswaran A, Troidl C, Mcnamara JW, Wilhelm J, Truschel T, Widmann L, Aslam M, Hamm CW, Sadayappan S, Lipps C. The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling. Cells 10, 2021.

June 2021

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