July 2021

Ali M, Mcauley MM, Lüchow S, Knapp S, Joerger AC, Ivarsson Y. Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs. Curr Res Struct Biol 3:41-50, 2021.
Brandes RP, Gilsbach R. Understanding Arteriosclerosis 2.0: Making Sense of Genetic Variants with scATAC. Circ Res 129:259-261, 2021. editorial
Buchmann GK, Schürmann C, Spaeth M, Abplanalp W, Tombor L, John D, Warwick T, Rezende F, Weigert A, Shah AM, Hansmann ML, Weissmann N, Dimmeler S, Schröder K, Brandes RP. The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice. Redox Biol 45:102050, 2021.
Cremer S, Jakob C, Berkowitsch A, Borgmann S, Pilgram L, Tometten L, Classen A, Wille K, Weidlich S, Gruener B, Dimmeler S, Massberg S, Rieg S, Zeiher AM. Elevated markers of thrombo-inflammatory activation predict outcome in patients with cardiovascular comorbidities and COVID-19 disease: insights from the LEOSS registry. Clin Res Cardiol 110:1029-1040, 2021.
Katsaouni N, Tashkandi A, Wiese L, Schulz MH. Machine learning based disease prediction from genotype data. Biol Chem, 2021. review
Lorenz NI, Sittig ACM, Urban H, Luger AL, Engel AL, Münch C, Steinbach JP, Ronellenfitsch MW. Activating transcription factor 4 mediates adaptation of human glioblastoma cells to hypoxia and temozolomide. Sci Rep 11:14161, 2021.
Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong KB, Ng W, Cinatl J, Geurink PP, Van Der Heden Van Noort GJ, Rajalingam K, Ciesek S, Hummer G, Dikic I. Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. J Biol Chem:100925, 2021.
Renker M, Fischer-Rasokat U, Walther C, Kim WK, Rixe J, Dörr O, Nef H, Rolf A, Möllmann H, Hamm CW. Evaluation of Patients for Percutaneous Edge-to-edge Mitral Valve Repair: Comparison of Cardiac Computed Tomography Angiography With Transesophageal Echocardiography. J Thorac Imaging, 2021.
Schaefer L, Dikic I. Autophagy: Instructions from the extracellular matrix. Matrix Biol, 2021.
Schmidt J, Oppermann E, Blaheta RA, Schreckenbach T, Lunger I, Rieger MA, Bechstein WO, Holzer K, Malkomes P. Carbonic-anhydrase IX expression is increased in thyroid cancer tissue and represents a potential therapeutic target to eradicate thyroid tumor-initiating cells. Mol Cell Endocrinol:111382, 2021.
Wagner JUG, Bojkova D, Shumliakivska M, Luxán G, Nicin L, Aslan GS, Milting H, Kandler JD, Dendorfer A, Heumueller AW, Fleming I, Bibli SI, Jakobi T, Dieterich C, Zeiher AM, Ciesek S, Cinatl J, Dimmeler S. Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants. Basic Res Cardiol 116:42, 2021.
Andreev S, Pantsar T, Tesch R, Kahlke N, El-Gokha A, Ansideri F, Grätz L, Romasco J, Sita G, Geibel C, Lämmerhofer M, Tarozzi A, Knapp S, Laufer SA, Koch P. Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. J Med Chem, 2021.
Boeder NF, Dörr O, Koepp T, Blachutzik F, Achenbach S, Elsässer A, Hamm CW, Nef HM. Acute Mechanical Performance of Magmaris vs. DESolve Bioresorbable Scaffolds in a Real-World Scenario. Front Cardiovasc Med 8:696287, 2021.
Errington N, Iremonger J, Pickworth JA, Kariotis S, Rhodes CJ, Rothman AM, Condliffe R, Elliot CA, Kiely DG, Howard LS, Wharton J, Thompson AaR, Morrell NW, Wilkins MR, Wang D, Lawrie A. A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine 69:103444, 2021.
Fischer-Rasokat U, Renker M, Liebetrau C, Weferling M, Rolf A, Hain A, Sperzel J, Choi YH, Hamm CW, Kim WK. Long-Term Survival in Patients with or without Implantable Cardioverter Defibrillator after Transcatheter Aortic Valve Implantation. J Clin Med 10, 2021.
Gamal AS, Hara H, Tomaniak M, Lunardi M, Gao C, Ono M, Kawashima H, Jüni P, Vranckx P, Windecker S, Hamm C, Steg PG, Onuma Y, Serruys PW. ‘Ticagrelor alone vs. dual antiplatelet therapy from 1 month after drug-eluting coronary stenting among patients with STEMI’: a post hoc analysis of the randomized GLOBAL LEADERS trial. Eur Heart J Acute Cardiovasc Care, 2021.
Hoffmann J, Luxán G, Abplanalp WT, Glaser SF, Rasper T, Fischer A, Muhly-Reinholz M, Potente M, Assmus B, John D, Zeiher AM, Dimmeler S. Post-myocardial infarction heart failure dysregulates the bone vascular niche. Nat Commun 12:3964, 2021.
Koch I, Andrade-Navarro M, Schulz MH, Zarnack K. Bioinformatics in theory and application – highlights of the 36th German Conference on Bioinformatics. Biol Chem, 2021. editorial
Kryvenko V, Wessendorf M, Tello K, Herold S, Morty RE, Seeger W, Vadász I. Hypercapnia-induces IRE1α-driven Endoplasmic Reticulum-associated Degradation of the Na,K-ATPase β-subunit. Am J Respir Cell Mol Biol, 2021.
Mathea S, Salah E, Tallant C, Chatterjee D, Berger BT, Konietzny R, Müller-Knapp S, Kessler BM, Knapp S. Conformational plasticity of the ULK3 kinase domain. Biochem J, 2021.
Sweatt AJ, Miyagawa K, Rhodes CJ, Taylor S, Del Rosario PA, Hsi A, Haddad F, Spiekerkoetter E, Bental-Roof M, Bland RD, Swietlik EM, Gräf S, Wilkins MR, Morrell NW, Nicolls MR, Rabinovitch M, Zamanian RT. Severe Pulmonary Arterial Hypertension is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency. Chest, 2021.
Ando K, Shih YH, Ebarasi L, Grosse A, Portman D, Chiba A, Mattonet K, Gerri C, Stainier DYR, Mochizuki N, Fukuhara S, Betsholtz C, Lawson ND. Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development. Dev Biol 479:11-22, 2021.
Andreadou I, Efentakis P, Frenis K, Daiber A, Schulz R. Thiol-based redox-active proteins as cardioprotective therapeutic agents in cardiovascular diseases. Basic Res Cardiol 116:44, 2021. review
Bacher S, Stekman H, Farah CM, Karger A, Kracht M, Schmitz ML. MEKK1-dependent activation of the CRL4 complex is important for DNA damage-induced degradation of p21 and DDB2 and cell survival. Mol Cell Biol:Mcb0008121, 2021.
Botros L, Jansen SMA, Ashek A, Spruijt OA, Tramper J, Noordegraaf AV, Aman J, Harms H, De Man FS, Huisman MC, Zhao L, Bogaard HJ. Application of [18F]FLT-PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers. Pulm Circ 11:20458940211028017, 2021.
Busch J, Moreno R, De La Vega L, Saul VV, Bacher S, Von Zweydorf F, Ueffing M, Weber A, Gloeckner CJ, Linne U, Kracht M, Schmitz ML. TRAF6 Phosphorylation Prevents Its Autophagic Degradation and Re-Shapes LPS-Triggered Signaling Networks. Cancers (Basel) 13, 2021.
Ehrlich K, Wilhelm J, Markart P, Weisser H, Wolff JC, Bein G, Pak O, Barreto G, Weissmann N, Schramm F, Seeger W, Schaefer L, Kuebler WM, Wygrecka M. Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community acquired pneumonia. Am J Physiol Lung Cell Mol Physiol, 2021.
Fischer-Rasokat U, Renker M, Bänsch C, Weferling M, Liebetrau C, Herrmann E, Liakopoulos O, Choi YH, Hamm CW, Kim WK. Effects of statins after transcatheter aortic valve implantation in key patient populations. J Cardiovasc Pharmacol, 2021.
Gabrielli NM, Mazzocchi LC, Kryvenko V, Tello K, Herold S, Morty RE, Grimminger F, Dada LA, Seeger W, Sznajder JI, Vadász I. TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia. Front Cell Dev Biol 9:689983, 2021.
Gerstmeier J, Possmayer AL, Bozkurt S, Hoffmann ME, Dikic I, Herold-Mende C, Burger MC, Münch C, Kögel D, Linder B. Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide. Cancers (Basel) 13, 2021.
Hoffmann M, Pachl E, Hartung M, Stiegler V, Baumbach J, Schulz MH, List M. SPONGEdb: a pan-cancer resource for competing endogenous RNA interactions. NAR Cancer 3:zcaa042, 2021.
Jakutis G, Stainier DYR. Genotype-Phenotype Relationships in the Context of Transcriptional Adaptation and Genetic Robustness. Annu Rev Genet, 2021.
Kaulich M, Link VM, Lapek JD, Jr., Lee YJ, Glass CK, Gonzalez DJ, Dowdy SF. A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition. Sci Rep 11:14736, 2021.
Keranov S, Dörr O, Jafari L, Liebetrau C, Keller T, Troidl C, Riehm J, Rutsatz W, Bauer P, Kriechbaum S, Voss S, Richter MJ, Tello K, Gall H, Ghofrani HA, Guth S, Seeger W, Hamm CW, Nef H. Osteopontin and galectin-3 as biomarkers of maladaptive right ventricular remodeling in pulmonary hypertension. Biomark Med, 2021.
Kesavan R, Frömel T, Zukunft S, Brüne B, Weigert A, Wittig I, Popp R, Fleming I. The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast Cancer. Int J Mol Sci 22, 2021.
Kim WK, Pellegrini C, Ludwig S, Möllmann H, Leuschner F, Makkar R, Leick J, Amat-Santos IJ, Dörr O, Breitbart P, Jimenez Diaz VA, Dabrowski M, Rudolph T, Avanzas P, Kaur J, Toggweiler S, Kerber S, Ranosch P, Regazzoli D, Frank D, Landes U, Webb J, Barbanti M, Purita P, Pilgrim T, Liska B, Tabata N, Rheude T, Seiffert M, Eckel C, Allali A, Valvo R, Yoon SH, Werner N, Nef H, Choi YH, Hamm CW, Sinning JM. Feasibility of Coronary Access in Patients With Acute Coronary Syndrome and Previous TAVR. JACC Cardiovasc Interv 14:1578-1590, 2021.
Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, Heilemann M, Dikic I. Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection. Cell Death Differ, 2021.
Nonga OE, Lavogina D, Enkvist E, Kestav K, Chaikuad A, Dixon-Clarke SE, Bullock AN, Kopanchuk S, Ivan T, Ekambaram R, Viht K, Knapp S, Uri A. Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules 26, 2021.
Qi H, Liu H, Pullamsetti SS, Günther S, Kuenne C, Atzberger A, Sommer N, Hadzic S, Günther A, Weissmann N, Zhou Y, Yuan X, Braun T. Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells is Required to Prevent Pulmonary Hypertension and COPD. Circulation, 2021.
Saraji A, Sydykov A, Schäfer K, Garcia-Castro CF, Henneke I, Alebrahimdehkordi N, Kosanovic D, Hadzic S, Guenther A, Hecker M, Ghofrani HA, Seeger W, Schermuly RT, Weissmann N, Sommer N, Pak O. PINK1-mediated Mitophagy Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension. Am J Respir Cell Mol Biol 65:226-228, 2021. letter
Schmid T, Brüne B. Prostanoids and Resolution of Inflammation – Beyond the Lipid-Mediator Class Switch. Front Immunol 12:714042, 2021. review
Sivaraj KK, Jeong HW, Dharmalingam B, Zeuschner D, Adams S, Potente M, Adams RH. Regional specialization and fate specification of bone stromal cells in skeletal development. Cell Rep 36:109352, 2021.
Ustjanzew A, Preussner J, Bentsen M, Kuenne C, Looso M. i2dash: Creation of Flexible, Interactive and Web-based Dashboards for Visualization of Omics Data. Genomics Proteomics Bioinformatics, 2021.
Valečka J, Camosseto V, Mcewan DG, Terawaki S, Liu Z, Strock E, Almeida CR, Su B, Dikic I, Liang Y, Gatti E, Pierre P. RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages. R Soc Open Sci 8:202333, 2021.
Wang F, Hadzic S, Roxlau ET, Fuehler B, Janise-Libawski A, Wimmer T, Lei B, Li SW, Weissmann N, Stieger K. Retinal tissue develops an inflammatory reaction to tobacco smoke and electronic cigarette vapor in mice. J Mol Med (Berl), 2021.

July 2021

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