December 2021

Kremer N, Rako Z, Douschan P, Gall H, Ghofrani HA, Grimminger F, Guth S, Naeije R, Rieth A, Schulz R, Seeger W, Tedford RJ, Vadász I, Vanderpool R, Wiedenroth CB, Richter MJ, Tello K. Unmasking right ventricular-arterial uncoupling during fluid challenge in pulmonary hypertension. J Heart Lung Transplant, 2021.
Werner N, Renker M, Dörr O, Bauer T, Nef H, Choi YH, Hamm CW, Zahn R, Kim WK. Anatomical suitability and off-label use of contemporary transcatheter heart valves. Int J Cardiol, 2021.
Cavender MA, Harrington RA, Stone GW, Steg PG, Gibson CM, Hamm CW, Price MJ, Lopes RD, Leonardi S, Deliargyris EN, Prats J, Mahaffey KW, White HD, Bhatt DL. Ischemic Events Occur Early in Patients Undergoing Percutaneous Coronary Intervention and Are Reduced With Cangrelor: Findings From CHAMPION PHOENIX. Circ Cardiovasc Interv.Circinterventions120010390, 2021.
Diehl V, Huber LS, Trebicka J, Wygrecka M, Iozzo RV, Schaefer L. The Role of Decorin and Biglycan Signaling in Tumorigenesis. Front Oncol.11:801801, 2021. Review
Elwakeel E, Weigert A. Breast Cancer CAFs: Spectrum of Phenotypes and Promising Targeting Avenues. Int J Mol Sci.22, 2021.review
Hansen L, Lohfink N, Vutukuri R, Kestner RI, Trautmann S, Hecht M, Wagner PV, Spitzer D, Khel MI, Macas J, Ferreirós N, Gurke R, Günther S, Pfeilschifter W, Devraj K. Endothelial sphingosine-1-phosphate receptor 4 regulates blood-brain barrier permeability and promotes a homeostatic endothelial phenotype. J Neurosci. 2021.
Kriechbaum SD, Vietheer JM, Wiedenroth CB, Rudolph F, Barde M, Wolter JS, Haas M, Fischer-Rasokat U, Weferling M, Rolf A, Hamm CW, Mayer E, Guth S, Keller T, Roller FC, Liebetrau C. Cardiac biomarkers as indicators of right ventricular dysfunction and recovery in chronic thromboembolic pulmonary hypertension patients after balloon pulmonary angioplasty therapy – a cardiac magnetic resonance imaging cohort study. Pulm Circ.11:20458940211056500, 2021.
Liu R, Krüger K, Pilat C, Fan W, Xiao Y, Seimetz M, Ringseis R, Baumgart-Vogt E, Eder K, Weissmann N, Mooren FC. Excessive Accumulation of Intracellular Ca(2+) After Acute Exercise Potentiated Impairment of T-cell Function. Front Physiol.12:728625, 2021.
Schaefer L. New Year Greetings from the Editor-in-Chief of the American Journal of Physiology-Cell Physiology. Am J Physiol Cell Physiol. 2021. editorial
Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba AE, Sander LE. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell. 2021.
Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D. The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. ACS Pharmacol Transl Sci.4:1794-1807, 2021.
Keranov S, Haen S, Vietheer J, Rutsatz W, Wolter JS, Kriechbaum SD, von Jeinsen B, Bauer P, Tello K, Richter M, Dörr O, Rieth AJ, Nef H, Hamm CW, Liebetrau C, Rolf A, Keller T. Application and Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio in Patients with Ischemic and Non-Ischemic Cardiomyopathy. Diagnostics (Basel).11, 2021.
Knoepp F, Wahl J, Andersson A, Kraut S, Sommer N, Weissmann N, Ramser K. A Microfluidic System for Simultaneous Raman Spectroscopy, Patch-Clamp Electrophysiology, and Live-Cell Imaging to Study Key Cellular Events of Single Living Cells in Response to Acute Hypoxia. Small Methods.5:e2100470, 2021.
Luciano V, Proschak E, Langer JD, Knapp S, Heering J, Marschalek R. Closantel is an allosteric inhibitor of human Taspase1. iScience.24:103524, 2021.
Mainka M, George S, Angioni C, Ebert R, Goebel T, Kampschulte N, Krommes A, Weigert A, Thomas D, Schebb NH, Steinhilber D, Kahnt AS. On the biosynthesis of specialized pro-resolving mediators in human neutrophils and the influence of cell integrity. Biochim Biophys Acta Mol Cell Biol Lipids.159093, 2021.
Nohl A, Seelmann C, Roenick R, Ohmann T, Lefering R, Brune B, Weichert V, Dudda M, The TraumaRegister D. Impact of DST (Daylight Saving Time) on Major Trauma: A European Cohort Study. Int J Environ Res Public Health.18, 2021.
Rabbat MG, Kwong RY, Heitner JF, Young AA, Shanbhag SM, Petersen SE, Selvanayagam JB, Berry C, Nagel E, Heydari B, Maceira AM, Shenoy C, Dyke C, Bilchick KC. The Future of Cardiac Magnetic Resonance Clinical Trials. JACC Cardiovasc Imaging. 2021. editorial
Rajpoot S, Solanki K, Kumar A, Zhang KYJ, Pullamsetti SS, Savai R, Faisal SM, Pan Q, Baig MS. In-Silico Design of a Novel Tridecapeptide Targeting Spike Protein of SARS-CoV-2 Variants of Concern. Int J Pept Res Ther.28:28, 2022.
Slišković I, Eich H, Müller-McNicoll M. Exploring the multifunctionality of SR proteins. Biochem Soc Trans. 2021.
White HD, Schwartz GG, Szarek M, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Goodman SG, Jukema JW, Loy M, Pagidipati N, Pordy R, Ristić AD, Zeiher AM, Wojdyla DM, Steg PG. Alirocumab after acute coronary syndrome in patients with a history of heart failure. Eur Heart J. 2021.
Yim YY, McDonald WH, Betke KM, Kaya A, Hyde K, Erreger K, Gilsbach R, Hein L, Hamm HE. Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α(2a)-adrenergic receptors. Sci Signal.14:eabc4970, 2021.
Zisiopoulou M, Berkowitsch A, Seppelt P, Zeiher AM, Vasa-Nicotera M. A Novel Method to Predict Mortality and Length of Stay after Transfemoral Transcatheter Aortic Valve Implantation. Medicina (Kaunas).57, 2021.
De Boer RA, Heymans S, Backs J, Carrier L, Coats AJS, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot JS, Knöll R, Kupatt C, Linke WA, Seidman CE, Tocchetti CG, Van Der Velden J, Walsh R, Seferovic PM, Thum T. Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: From molecular mechanisms to therapeutic targets. Eur J Heart Fail, 2021.
Erdogdu U, Dolgikh N, Laszig S, Särchen V, Meister MT, Wanior M, Knapp S, Boedicker C. Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells. Neoplasia 24:109-119, 2021.
Roller FC, Schüssler A, Hasse A, Kriechbaum S, Richter M, Guth S, Tello K, Breithecker A, Liebetrau C, Hamm CW, Mayer E, Seeger W, Krombach GA, Wiedenroth CB. Effects of BPA on right ventricular mechanical dysfunction in patients with inoperable CTEPH – A cardiac magnetic resonance study. Eur J Radiol 147:110111, 2021.
Weferling M, Rolf A, Fischer-Rasokat U, Liebetrau C, Renker M, Choi YH, Hamm CW, Dey D, Kim WK. Epicardial fat volume is associated with preexisting atrioventricular conduction abnormalities and increased pacemaker implantation rate in patients undergoing transcatheter aortic valve implantation. Int J Cardiovasc Imaging, 2021.
Halawa S, Pullamsetti SS, Bangham CRM, Stenmark KR, Dorfmüller P, Frid MG, Butrous G, Morrell NW, De Jesus Perez VA, Stuart DI, O’gallagher K, Shah AM, Aguib Y, Yacoub MH. Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective. Nat Rev Cardiol:1-18, 2021. review
Kariotis S, Jammeh E, Swietlik EM, Pickworth JA, Rhodes CJ, Otero P, Wharton J, Iremonger J, Dunning MJ, Pandya D, Mascarenhas TS, Errington N, Thompson AaR, Romanoski CE, Rischard F, Garcia JGN, Yuan JX, An TS, Desai AA, Coghlan G, Lordan J, Corris PA, Howard LS, Condliffe R, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort S, Gräf S, Morrell NW, Wilkins MR, Lawrie A, Wang D. Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nat Commun 12:7104, 2021.
Kim WK, Nef H, Choi YH, Hamm CW. First-in-Man Transfemoral Stent-in-Valve Implantation as Bailout for Failed Transcatheter Heart Valve Implantation: Proof of Concept. JACC Cardiovasc Interv 14:2640-2642, 2021. letter
Potapov EV, Politis N, Karck M, Weyand M, Tandler R, Walther T, Emrich F, Reichenspurrner H, Bernhardt A, Barten MJ, Svenarud P, Gummert J, Sef D, Doenst T, Tsyganenko D, Loforte A, Schoenrath F, Falk V. Results from a multicentre evaluation of plug use for left ventricular assist device explantation. Interact Cardiovasc Thorac Surg, 2021.
Stamatiades GA, Toufaily C, Kim HK, Zhou X, Thompson IR, Carroll RS, Chen M, Weinstein LS, Offermanns S, Boehm U, Bernard DJ, Kaiser UB. Deletion of Gαq/11 or Gαs proteins in gonadotropes differentially affects gonadotropin production and secretion in mice. Endocrinology, 2021.
Wilkins MR, Mckie MA, Law M, Roussakis AA, Harbaum L, Church C, Coghlan JG, Condliffe R, Howard LS, Kiely DG, Lordan J, Rothman A, Suntharalingam J, Toshner M, Wort SJ, Villar SS. Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single-arm efficacy. Pulm Circ 11:20458940211052823, 2021.
Wygrecka M, Birnhuber A, Seeliger B, Michalick L, Pak O, Schultz AS, Schramm F, Zacharias M, Gorkiewicz G, David S, Welte T, Schmidt JJ, Weissmann N, Schermuly RT, Barreto G, Schaefer L, Markart P, Brack MC, Hippenstiel S, Kurth F, Sander L, Witzenrath M, Kuebler W, Kwapiszewska G, Preissner KT. Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19. Blood Adv, 2021.
Birot A, Kus K, Priest E, Al Alwash A, Castello A, Mohammed S, Vasiljeva L, Kilchert C. RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response. Life Sci Alliance 5, 2022.
Frömel T, Naeem Z, Pirzeh L, Fleming I. Cytochrome P450-derived fatty acid epoxides and diols in angiogenesis and stem cell biology. Pharmacol Ther:108049, 2021. review
Jandl K, Mutgan AC, Eller K, Schaefer L, Kwapiszewska G. The basement membrane in the cross-roads between the lung and kidney. Matrix Biol, 2021. review
Kaneshige A, Kaji T, Zhang L, Saito H, Nakamura A, Kurosawa T, Ikemoto-Uezumi M, Tsujikawa K, Seno S, Hori M, Saito Y, Matozaki T, Maehara K, Ohkawa Y, Potente M, Watanabe S, Braun T, Uezumi A, Fukada SI. Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load. Cell Stem Cell, 2021.
Piayda K, Bauer T, Beckmann A, Bekeredjian R, Bleiziffer S, Ensminger S, Frerker C, Möllmann H, Walther T, Balaban Ü, Herrmann E, Hamm C, Beyersdorf F, Lichtenberg A, Zeus T, Mehdiani A. Procedural Results of Patients Undergoing Transcatheter Aortic Valve Implantation With Aortic Annuli Diameter ≥26 mm: insights from the German Aortic Valve Registry. Am J Cardiol, 2021.
Schäfer JA, Bozkurt S, Michaelis JB, Klann K, Münch C. Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery. Mol Cell, 2021.
Schumann L, Wilken-Schmitz A, Trautmann S, Vogel A, Schreiber Y, Hahnefeld L, Gurke R, Geisslinger G, Tegeder I. Increased Fat Taste Preference in Progranulin-Deficient Mice. Nutrients 13, 2021.
Stöhr MR, Günther A, Majeed RW. The Collaborative Metadata Repository (CoMetaR) Web App: Quantitative and Qualitative Usability Evaluation. JMIR Med Inform 9:e30308, 2021.
Vietheer J, Lehmann L, Unbehaun C, Fischer-Rasokat U, Wolter JS, Kriechbaum S, Weferling M, Von Jeinsen B, Hain A, Liebetrau C, Hamm CW, Keller T, Rolf A. CMR-derived myocardial strain analysis differentiates ischemic and dilated cardiomyopathy-a propensity score-matched study. Int J Cardiovasc Imaging, 2021.
Wein B, Zaczkiewicz M, Graf M, Zimmermann O, Gori T, Nef HM, Kastner J, Mehilli J, Richardt G, Wöhrle J, Achenbach S, Riemer T, Hamm C, Torzewski J. No difference in 30-day outcome and quality of life in transradial versus transfemoral access – Results from the German Austrian ABSORB registry (GABI-R). Cardiovasc Revasc Med, 2021.
Yogeswaran A, Tello K, Lund J, Klose H, Harbaum L, Sommer N, Oqueka T, Hennigs JK, Grimminger F, Seeger W, Ghofrani HA, Richter MJ, Gall H. Risk assessment in pulmonary hypertension based on routinely measured laboratory parameters. J Heart Lung Transplant, 2021.
Zhou J, Dabiri Y, Gama-Brambila RA, Ghafoory S, Altinbay M, Mehrabi A, Golriz M, Blagojevic B, Reuter S, Han K, Seidel A, Đikić I, Wölfl S, Cheng X. pVHL-mediated SMAD3 degradation suppresses TGF-β signaling. J Cell Biol 221, 2022.

December 2021

News