December 2019

New in PubMed from CPI Faculty:

December 2019

 

  1. ARuiz-Meana M, Boengler K, Garcia-Dorado D, Hausenloy DJ, Kaambre T, Kararigas G, Perrino C, Schulz R, Ytrehus K. geing, sex and cardioprotection.  Br J Pharmacol. 2019 Dec 20. doi: 10.1111/bph.14951. [Epub ahead of print] Review. PMID: 31863453 [PubMed – as supplied by publisher]
  2. Aslam M, Troidl C, Tanislav C, Rohrbach S, Gündüz D, Hamm CW.Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function. Int J Mol Sci. 2019 Dec 18;21(1). pii: E2. doi: 10.3390/ijms21010002. PMID: 31861297 [PubMed – in process]
  3. Chang CC, Chichareon P, Modolo R, Takahashi K, Kogame N, Tomaniak M, Gao C, Royaards KJ, Cequier A, Oldroyd K, Steg PG, Hamm C, Jüni P, Valgimigli M, Windecker S, Onuma Y, Stables RH, Jan van Geuns R, Serruys PW. Association between post-percutaneous coronary intervention bivalirudin infusion and net adverse clinical events: a post hoc analysis of the GLOBAL LEADERS study. Eur Heart J Cardiovasc Pharmacother. 2019 Dec 9. pii: pvz051. doi: 10.1093/ehjcvp/pvz051. [Epub ahead of print] PMID: 31841136 [PubMed – as supplied by publisher]
  4. Dos Santos LRB, Fleming I. Role of cytochrome P450-derived, polyunsaturated fatty acid mediators in diabetes and the metabolic syndrome.  Prostaglandins Other Lipid Mediat. 2019 Dec 31:106407. doi: 10.1016/j.prostaglandins.2019.106407. [Epub ahead of print] Review. PMID: 31899373 [PubMed – as supplied by publisher]
  5. Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos Y Schnitzler M. Helix 8 is the essential structural motif of mechanosensitive GPCRs. Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0. PMID: 31857598 [PubMed – in process]
  6. Fukuda R, Aharonov A, Ong YT, Stone OA, El-Brolosy M, Maischein HM, Potente M, Tzahor E, Stainier DY. Metabolic modulation regulates cardiac wall morphogenesis in zebrafish. Elife. 2019 Dec 23;8. pii: e50161. doi: 10.7554/eLife.50161. [Epub ahead of print] PMID: 31868165 [PubMed – as supplied by publisher]
  7. Garg S, Chichareon P, Kogame N, Takahashi K, Modolo R, Chang CC, Tomaniak M, Fath-Ordoubadi F, Anderson R, Oldroyd KG, Stables RH, Kukreja N, Chowdhary S, Galasko G, Hoole S, Zaman A, Hamm CW, Steg PG, Jüni P, Valgimigli M, Windecker S, Onuma Y, Serruys PW. Impact of established cardiovascular disease on outcomes in the randomized global leaders trial.Catheter Cardiovasc Interv. 2019 Dec 19. doi: 10.1002/ccd.28649. [Epub ahead of print] PMID: 31854112 [PubMed – as supplied by publisher]
  8. Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, Segarra M, Ruiz de Almodóvar C, Acker-Palmer A. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. Elife. 2019 Dec 23;8. pii: e49819. doi: 10.7554/eLife.49819. PMID: 31868584 [PubMed – in process]
  9. Hoffmann J, Fišer K, Liebetrau C, Staubach N, Kost D, Voss S, Heiden AZ, Dörr O, Lipps C, Nef HM, Möllmann H, Hamm CW, Keller T, Troidl C. High-Content Immunophenotyping and Hierarchical Clustering Reveal Sources of Heterogeneity and New Surface Markers of Human Blood Monocyte Subsets.  Thromb Haemost. 2019 Dec 30. doi: 10.1055/s-0039-1700871. [Epub ahead of print] PMID: 31887780 [PubMed – as supplied by publisher]
  10. Isobe J, Maeda S, Obata Y, Iizuka K, Nakamura Y, Fujimura Y, Kimizuka T, Hattori K, Kim YG, Morita T, Kimura I, Offermanns S, Adachi T, Nakao A, Kiyono H, Takahashi D, Hase K. Commensal-bacteria-derived butyrate promotes the T cell-independent IgA response in the colon. Int Immunol. 2019 Dec 20. pii: dxz078. doi: 10.1093/intimm/dxz078. [Epub ahead of print] PMID: 31858119 [PubMed – as supplied by publisher]
  11. Klann K, Tascher G, Münch C. Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α. Mol Cell. 2019 Nov 27. pii: S1097-2765(19)30839-1. doi: 10.1016/j.molcel.2019.11.010. [Epub ahead of print] PMID: 31812349 [PubMed – as supplied by publisher]
  12. Klotzsche-von Ameln A, Cremer S, Hoffmann J, Schuster P, Khedr S, Korovina I, Troullinaki M, Neuwirth A, Sprott D, Chatzigeorgiou A, Economopoulou M, Orlandi A, Hain A, Zeiher AM, Deussen A, Hajishengallis G, Dimmeler S, Chavakis T, Chavakis E. Erratum to: Endogenous developmental endothelial locus-1 limits ischaemia-related angiogenesis by blocking inflammation.  Thromb Haemost. 2019 Dec 16. doi: 10.1055/s-0039-1696711. [Epub ahead of print] No abstract available. PMID: 31842234 [PubMed – as supplied by publisher]
  13. Knoepp F, Ashley Z, Barth D, Baldin JP, Jennings M, Kazantseva M, Saw EL, Katare R, Alvarez de la Rosa D, Weissmann N, Fronius M. Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC. Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 201911243. doi: 10.1073/pnas.1911243117. [Epub ahead of print] PMID: 31871197 [PubMed – as supplied by publisher]
  14. Lanz J, Kim WK, Walther T, Burgdorf C, Möllmann H, Linke A, Redwood S, Thilo C, Hilker M, Joner M, Thiele H, Conzelmann L, Conradi L, Kerber S, Schymik G, Prendergast B, Husser O, Stortecky S, Heg D, Jüni P, Windecker S, Pilgrim T; Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial.  SCOPE I investigators. Lancet. 2019 Nov 2;394(10209):1619-1628. doi: 10.1016/S0140-6736(19)32220-2. Epub 2019 Sep 27. PMID: 31570258 [PubMed – indexed for MEDLINE]
  15. Li H, Kilgallen AB, Münzel T, Wolf E, Lecour S, Schulz R, Daiber A, Van Laake LW. Influence of mental stress and environmental toxins on circadian clocks – implications for redox regulation of the heart and cardioprotection.Br J Pharmacol. 2019 Dec 12. doi: 10.1111/bph.14949. [Epub ahead of print] Review. PMID: 31833063 [PubMed – as supplied by publisher]
  16. Lissoni A, Hulpiau P, Martins-Marques T, Wang N, Bultynck G, Schulz R, Witschas K, Girao H, De Smet M, Leybaert L. RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes. Cardiovasc Res. 2019 Dec 16. pii: cvz340. doi: 10.1093/cvr/cvz340. [Epub ahead of print] PMID: 31841141 [PubMed – as supplied by publisher]
  17. Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, Haverkamp S, Mann R, Martin-Villalba A, Schuman EM, Acker-Palmer A, Ruiz de Almodóvar C. VEGF/VEGFR2 signaling regulates hippocampal axon branching during development.  Elife. 2019 Dec 23;8. pii: e49818. doi: 10.7554/eLife.49818. PMID: 31868583 [PubMed – in process]
  18. Moreno-Domínguez A, Ortega-Sáenz P, Gao L, Colinas O, García-Flores P, Bonilla-Henao V, Aragonés J, Hüttemann M, Grossman LI, Weissmann N, Sommer N, López-Barneo J. Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. Sci Signal. 2019 Dec 17. pii: eaay9452. doi: 10.1126/scisignal.aay9452. [Epub ahead of print] PMID: 31848220 [PubMed – as supplied by publisher]
  19. Nagel E, Berry C. Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease N Engl J Med. 2019 Dec 5;381(23):2277-2278. doi: 10.1056/NEJMc1913968. No abstract available. PMID: 31801003 [PubMed – indexed for MEDLINE] Reply
  20. Ni X, Heidenreich D, Christott T, Bennett J, Moustakim M, Brennan PE, Fedorov O, Knapp S, Chaikuad A. Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1.ACS Med Chem Lett. 2019 Nov 25;10(12):1661-1666. doi: 10.1021/acsmedchemlett.9b00460. eCollection 2019 Dec 12. PMID: 31857843 [PubMed]
  21. Nikitopoulou I, Manitsopoulos N, Kotanidou A, Tian X, Petrovic A, Magkou C, Ninou I, Aidinis V, Schermuly RT, Kosanovic D, Orfanos SE. Orotracheal treprostinil administration attenuates bleomycin-induced lung injury, vascular remodeling, and fibrosis in mice. Pulm Circ. 2019 Nov 15;9(4):2045894019881954. doi: 10.1177/2045894019881954. eCollection 2019 Oct-Dec. PMID: 31819797 [PubMed]
  22. Pan C, Schoppe O, Parra-Damas A, Cai R, Todorov MI, Gondi G, von Neubeck B, Böğürcü-Seidel N, Seidel S, Sleiman K, Veltkamp C, Förstera B, Mai H, Rong Z, Trompak O, Ghasemigharagoz A, Reimer MA, Cuesta AM, Coronel J, Jeremias I, Saur D, Acker-Palmer A, Acker T, Garvalov BK, Menze B, Zeidler R, Ertürk A. Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body. Cell. 2019 Dec 12;179(7):1661-1676.e19. doi: 10.1016/j.cell.2019.11.013. PMID: 31835038 [PubMed – in process]
  23. Panta CR, Ruisanchez É, Móré D, Dancs PT, Balogh A, Fülöp Á, Kerék M, Proia RL, Offermanns S, Tigyi GJ, Benyó Z. Sphingosine-1-Phosphate Enhances α1-Adrenergic Vasoconstriction via S1P2-G12/13-ROCK Mediated Signaling. Int J Mol Sci . 2019 Dec 17;20(24). pii: E6361. doi: 10.3390/ijms20246361.PMID: 31861195 [PubMed – in process]
  24. Pardali E, Dimmeler S, Zeiher AM, Rieger MA. Clonal hematopoiesis, aging and cardiovascular diseases.  Exp Hematol. 2019 Dec 28. pii: S0301-472X(19)31241-X. doi: 10.1016/j.exphem.2019.12.006. [Epub ahead of print] PMID: 31891750 [PubMed – as supplied by publisher]
  25. Pathan F, Zainal Abidin HA, Vo QH, Zhou H, D’Angelo T, Elen E, Negishi K, Puntmann VO, Marwick TH, Nagel E. Left atrial strain: a multi-modality, multi-vendor comparison study. Eur Heart J Cardiovasc Imaging. 2019 Dec 17. pii: jez303. doi: 10.1093/ehjci/jez303. [Epub ahead of print] PMID: 31848575 [PubMed – as supplied by publisher]
  26. Scherm MG, Serr I, Zahm AM, Schug J, Bellusci S, Manfredini R, Salb VK, Gerlach K, Weigmann B, Ziegler AG, Kaestner KH, Daniel C. miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes. Nat Commun. 2019 Dec 13;10(1):5697. doi: 10.1038/s41467-019-13587-3. PMID: 31836704 [PubMed – in process]
  27. Schnieder J, Mamazhakypov A, Birnhuber A, Wilhelm J, Kwapiszewska G, Ruppert C, Markart P, Wujak L, Rubio K, Barreto G, Schaefer L, Wygrecka M. Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores.  Matrix Biol. 2019 Dec 10. pii: S0945-053X(19)30399-3. doi: 10.1016/j.matbio.2019.12.001. [Epub ahead of print] PMID: 31841706 [PubMed – as supplied by publisher]
  28. Song C, Liu L, Chen J, Hu Y, Li J, Wang B, Bellusci S, Chen C, Dong N. Evidence for the critical role of the PI3K signaling pathway in particulate matter-induced dysregulation of the inflammatory mediators COX-2/PGE2 and the associated epithelial barrier protein Filaggrin in the bronchial epithelium. Cell Biol Toxicol. 2019 Dec 28. doi: 10.1007/s10565-019-09508-1. [Epub ahead of print] PMID: 31884678 [PubMed – as supplied by publisher]
  29. Takahashi K, Kogame N, Tomaniak M, Chichareon P, Chang CC, Modolo R, Benit E, Liebetrau C, Janssens L, Ferrario M, Zurakowski A, van Geuns RJ, Dominici M, Huber K, Buszman P, Bolognese L, Tumscitz C, Żmudka K, Aminian A, Vrolix M, Petrov I, Wykrzykowska JJ, de Winter RJ, Hamm C, Steg PG, Onuma Y, Valgimigli M, Windecker S, Vranckx P, Garg S, Serruys PW. Impact of recruitment and retention on all-cause mortality in a large all-comers randomised controlled trial: insights from the GLOBAL LEADERS trial. Clin Res Cardiol. 2019 Dec 11. doi: 10.1007/s00392-019-01585-w. [Epub ahead of print] PMID: 31828504 [PubMed – as supplied by publisher]
  30. Tomaniak M, Chichareon P, Modolo R, Takahashi K, Chang CC, Kogame N, Spitzer E, Buszman PE, van Geuns RM, Valkov V, Steinwender C, Geisler T, Prokopczuk J, Sabaté M, Zmudka K, Rademaker-Havinga T, Tijssen JGP, Jüni P, Hamm C, Steg PG, Onuma Y, Vranckx P, Valgimigli M, Windecker S, Baber U, Anderson R, Dominici M, Serruys PW. Ticagrelor Monotherapy Beyond One Month after PCI in ACS or Stable CAD in Elderly Patients Aged Above 75 Years: a Prespecified Analysis of the Randomized GLOBAL LEADERS Trial. EuroIntervention. 2019 Dec 17. pii: EIJ-D-19-00699. doi: 10.4244/EIJ-D-19-00699. [Epub ahead of print] PMID: 31845894 [PubMed – as supplied by publisher]
  31. Tomaniak M, Chichareon P, Takahashi K, Kogame N, Modolo R, Chang CC, Spitzer E, Neumann FJ, Plante S, Hernández Antolin R, Jambrik Z, Gelev V, Brunel P, Konteva M, Beygui F, Morelle JF, Filipiak KJ, van Geuns RJ, Soliman O, Tijssen J, Rademaker-Havinga T, Storey RF, Hamm C, Steg PG, Windecker S, Onuma Y, Valgimigli M, Serruys PW. Impact of chronic obstructive pulmonary disease and dyspnoea on clinical outcomes in ticagrelor treated patients undergoing percutaneous coronary intervention in the randomized GLOBAL LEADERS trial. Eur Heart J Cardiovasc Pharmacother. 2019 Dec 9. pii: pvz052. doi: 10.1093/ehjcvp/pvz052. [Epub ahead of print] PMID: 31876907 [PubMed – as supplied by publisher]
  32. Wagner JUG, Pham MD, Nicin L, Hammer M, Bottermann K, Yuan T, Sharma R, John D, Muhly-Reinholz M, Tombor L, Hardt M, Madl J, Dimmeler S, Krishnan J. Dissection of heterocellular cross-talk in vascularized cardiac tissue mimetics.  J Mol Cell Cardiol. 2019 Dec 19. pii: S0022-2828(19)30395-5. doi: 10.1016/j.yjmcc.2019.12.005. [Epub ahead of print] PMID: 31866374 [PubMed – as supplied by publisher]
  33. Zuo H, Li R, Ma F, Jiang J, Miao K, Li H, Nagel E, Tadic M, Wang H, Wang DW. Temporal echocardiography findings in patients with fulminant myocarditis: beyond ejection fraction decline. Front Med. 2019 Dec 19. doi: 10.1007/s11684-019-0713-9. [Epub ahead of print] PMID: 31858367 [PubMed – as supplied by publisher]
  34. Lv YQ, Wu J, Li XK, Zhang JS, Bellusci S.Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury. Front Cell Dev Biol. 2019 Dec 10;7:326. doi: 10.3389/fcell.2019.00326. eCollection 2019. Review. PMID: 31921841 [PubMed]
  35. Husain-Syed F, Birk HW, Tello K, Richter MJ, Ronco C, McCullough PA, Schörmann T, Ferrari F, Yücel G, Yazdani B, Walmrath HD, Seeger W, Gall H, Ghofrani HA.Alterations in Doppler-derived renal venous stasis index during recompensation of right heart failure and fluid overload in a patient with pulmonary hypertension. Rev Cardiovasc Med. 2019 Dec 30;20(4):263-266. doi: 10.31083/j.rcm.2019.04.564. PMID: 31912717 [PubMed – in process
  36. Andreadou I, Schulz R, Badimon L, Adameova A, Kleinbogard P, Lecour S, Nikolaou PE, Falcao-Pires I, Vilahur G, Woudberg N, Heusch G and Ferdinandy P. Hyperlipidaemia and cardioprotection: animal models for translational studies. Br J Pharmacol. 2019]
  37. Bibli SI, Hu J, Leisegang MS, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes RP, Papapetropoulos A, Sigala F and Fleming I. Shear stress regulates cystathionine gamma lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation. Redox Biol. 2019;28:101379.
  38. Didiasova M, Wujak L, Schaefer L and Wygrecka M. Factor XII in coagulation, inflammation and beyond. Cell Signal. 2018;51:257-265.
  39. Fischer-Rasokat U, Renker M, Liebetrau C, Weferling M, Rolf A, Doss M, Mollmann H, Walther T, Hamm CW and Kim WK. Outcome of patients with heart failure after transcatheter aortic valve implantation. PLoS One. 2019;14:e0225473.
  40. Heinke R, Pathan F, Le M, D’angelo T, Winau L, Arendt C, Vogl TJ, Zeiher A, Nagel E and Puntmann VO. Towards standardized postprocessing of global longitudinal strain by feature tracking – OptiStrain CMR-FT study. BMC Cardiovasc Disord. 2019;19:267.
  41. Kim HT, Yin W, Nakamichi Y, Panza P, Grohmann B, Buettner C, Guenther S, Ruppert C, Kobayashi Y, Guenther A and Stainier DYR. WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. Proc Natl Acad Sci U S A. 2019.
  42. Lechner C, Flasshoff M, Falke H, Preu L, Loaec N, Meijer L, Knapp S, Chaikuad A and Kunick C. [b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors. Molecules. 2019;24.
  43. Murray MK, Hofmann E, De Rosa R, Mas-Peiro S, Seppelt P, Walther T, Zeiher AM, Fichtlscherer S and Vasa-Nicotera M. Life beyond 5 Years after TAVI: Patients‘ Perceived Health Status and Long-Term Outcome after Transcatheter Aortic Valve Implantation. J Interv Cardiol. 2019;2019:4292987.
  44. Parnham MJ and Geisslinger G. Pharmacological plasticity-How do you hit a moving target? Pharmacol Res Perspect. 2019;7:e00532.
  45. Shahriari F, Satarian L, Moradi S, Zarchi AS, Gunther S, Kamal A, Totonchi M, Mowla SJ, Braun T and Baharvand H. MicroRNA profiling reveals important functions of miR-125b and let-7a during human retinal pigment epithelial cell differentiation. Exp Eye Res. 2019;190:107883.
  46. Syed SN, Frank AC, Raue R and Brune B. MicroRNA-A Tumor Trojan Horse for Tumor-Associated Macrophages. Cells. 2019;8.
  47. Wagner JUG and Dimmeler S. Cellular cross-talks in the diseased and aging heart. J Mol Cell Cardiol. 2019